Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
PROSPECTIVE, RANDOMIZED, CONTROLLED-STUDY OF THE EFFECT OF HORMONE REPLACEMENT THERAPY ON PERIPHERAL-BLOOD FLOW VELOCITY IN POSTMENOPAUSAL WOMEN
Autore:
LAU TK; WAN D; YIM SF; SANDERSON JE; HAINES CJ;
Indirizzi:
CHINESE UNIV HONG KONG,PRINCE WALES HOSP,DEPT OBSTET & GYNAECOL SHATIN NEW TERRITORIES HONG KONG CHINESE UNIV HONG KONG,PRINCE WALES HOSP,DEPT MED SHATIN NEW TERRITORIES HONG KONG
Titolo Testata:
Fertility and sterility
fascicolo: 2, volume: 70, anno: 1998,
pagine: 284 - 288
SICI:
0015-0282(1998)70:2<284:PRCOTE>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESTROGEN THERAPY; FOLLOW-UP; DISEASE; ARTERY;
Keywords:
HORMONE REPLACEMENT THERAPY; PERIPHERAL ARTERY; PULSATILITY INDEX;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
T.K. Lau et al., "PROSPECTIVE, RANDOMIZED, CONTROLLED-STUDY OF THE EFFECT OF HORMONE REPLACEMENT THERAPY ON PERIPHERAL-BLOOD FLOW VELOCITY IN POSTMENOPAUSAL WOMEN", Fertility and sterility, 70(2), 1998, pp. 284-288

Abstract

Objective: To investigate the effect of different types and methods of delivery of hormone replacement therapy (HRT) on peripheral vascularflow velocity in postmenopausal women. Design: A prospective, randomized, operator-blinded, controlled study. Setting: A hormone replacement clinic in a university teaching hospital. Patient(s): Sixty-eight women who had undergone surgical menopause. Intervention(s): No treatment, oral estrogen, continuous combined estrogen and progestogen, or percutaneous estrogen. Main Outcome Measure(s): The pulsatility indices of the brachial, dorsalis pedis, popliteal, and radial arteries were measured under standardized conditions before the commencement of HRT and after 2 and 6 months of treatment. Serum E-2 levels were measured ateach visit. Result(s): There was an inverse correlation between the serum E-2 levels and the pulsatility indices. There was a significant reduction in the pulsatility index in at least one of the four arteriesafter 2 months of HRT in all the treatment groups but not in the control group. The effect of HRT on the pulsatility index persisted until the completion of the study in all the treatment groups. Conclusion(s): These results confirm that the administration of HRT is associated with a reduction of the pulsatility index, and hence an increase in blood flow in the peripheral arteries; this change in the pulsatility index is related directly to serum E-2 levels. The percutaneous route of administration of estrogen was at least as effective as oral treatmentin improving peripheral vascular flow velocity. The beneficial effectof estrogen was not affected by the addition of a progestogen. (Fertil Steril(R) 1998:70:284-8. (C)1998 by American Society for Reproductive Medicine.).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 07:45:05