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Titolo:
ENHANCEMENT OF VENTRICULAR GRADIENT VARIABILITY DURING ACUTE MYOCARDIAL-ISCHEMIA
Autore:
HORINAKA S; YAMAMOTO H;
Indirizzi:
DOKKYO UNIV,SCH MED,DEPT MED,880 KITAKOBAYASHI MIBU TOCHIGI 3210293 JAPAN
Titolo Testata:
International journal of cardiology
fascicolo: 2, volume: 65, anno: 1998,
pagine: 173 - 180
SICI:
0167-5273(1998)65:2<173:EOVGVD>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; ANESTHETIZED PIG; TIME COURSE; ST SEGMENT; ENDOCARDIUM; ARRHYTHMIAS; EPICARDIUM; FLOW; DOG; REPOLARIZATION;
Keywords:
VENTRICULAR GRADIENT VARIABILITY; MONOPHASIC ACTION POTENTIAL; ACUTE MYOCARDIAL ISCHEMIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
S. Horinaka e H. Yamamoto, "ENHANCEMENT OF VENTRICULAR GRADIENT VARIABILITY DURING ACUTE MYOCARDIAL-ISCHEMIA", International journal of cardiology, 65(2), 1998, pp. 173-180

Abstract

We evaluated the influence of local myocardial ischemia induced by experimental coronary stenosis on the ventricular gradients (VGs) and determined whether changes of VG were related to the alterations of monophasic action potentials (MAPs). The coronary flow was reduced to 50% in the left anterior descending coronary artery for 30 min in nine dogs. The VG and MAP of consecutive heartbeats over a 20-s interval were obtained from McFee and Parungao body surface leads and a suction electrode on the ischemic and non-ischemic regions. The coefficients of variation of VG and MAP parameters were calculated as indices of variability. The coefficients of variation of the VG magnitude and the MAP area in the ischemic region were greater at 5 min after partial occlusion than in the control period (P<0.05, P<0.01, respectively). There wasa significant correlation between the coefficient of Variation of theVG magnitude and the coefficient of variation of the MAP area in the ischemic region (r=0.707, P<0.0001) but not in the non-ischemic region. VG variability was enhanced during acute regional ischemia of the ventricular myocardium. VG variability may be caused by enhanced electrical alteration of the MAP in ischemic myocardium. (C) 1998 Elsevier Science Ireland Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 11:52:21