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Titolo:
SOLUBLE FAS IN THE SERUM OF PATIENTS WITH NON-HODGKINS-LYMPHOMA - HIGHER CONCENTRATIONS IN ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA
Autore:
YUFU Y; CHOI I; HIRASE N; TOKORO A; NOGUCHI Y; GOTO T; UIKE N; KOZURU M;
Indirizzi:
NATL KYUSHU CANC CTR,DEPT HEMATOL,MINAMI KU,3-1-1 NOTAME FUKUOKA 815 JAPAN KYUSHU UNIV,FAC MED,DEPT INTERNAL MED 3 FUKUOKA 812 JAPAN
Titolo Testata:
American journal of hematology
fascicolo: 4, volume: 58, anno: 1998,
pagine: 334 - 336
SICI:
0361-8609(1998)58:4<334:SFITSO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
LYMPHOPROLIFERATIVE SYNDROME; GENE-MUTATIONS; LYMPHADENOPATHY; AUTOIMMUNITY; APOPTOSIS;
Keywords:
SOLUBLE FAS; APOPTOSIS; NON-HODGKINS LYMPHOMA; ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
Y. Yufu et al., "SOLUBLE FAS IN THE SERUM OF PATIENTS WITH NON-HODGKINS-LYMPHOMA - HIGHER CONCENTRATIONS IN ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA", American journal of hematology, 58(4), 1998, pp. 334-336

Abstract

The soluble form of Fas (sFas) can block apoptosis induced by the Fasligand in vitro. A recent report demonstrated that mice injected withsFas displayed autoimmune features, Therefore, an elevated serum concentration of sFas may be associated with lymphoproliferation and autoimmune diseases. We measured the serum concentrations of sFas in 77 patients with non-Hodgkin's lymphoma (NHL) [8 angioimmunoblastic T-cell lymphoma (AIL), 12 T-cell NHL, 53 B-cell NHL, and 4 natural killer-cellNHL], Elevated concentrations of sFas were detected only in AIL, which is frequently accompanied by autoimmune diseases (P < 0.005 comparedwith age-matched controls). A possible association of sFas and autoimmune features in AIL is discussed, (C) 1998 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 12:41:31