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Titolo:
EFFECT OF IMMUNONUTRITION ON VIRULENCE STRATEGIES IN BACTERIA
Autore:
ALVERDY J; STERN E;
Indirizzi:
5841 S MARYLAND,MC-6090 CHICAGO IL 60637 UNIV CHICAGO,PRITZKER SCH MED,DEPT SURG CHICAGO IL 60637
Titolo Testata:
Nutrition
fascicolo: 7-8, volume: 14, anno: 1998,
pagine: 580 - 584
SICI:
0899-9007(1998)14:7-8<580:EOIOVS>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESCHERICHIA-COLI; PILUS; ADHERENCE; TRANSLOCATION; EXPRESSION; ADHESINS; BARRIER; CELLS; GUT; K99;
Keywords:
BACTERIAL ADHERENCE; MUCOSA EPITHELIA; GASTROINTESTINAL TRACT; BACTERIAL VIRULENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
J. Alverdy e E. Stern, "EFFECT OF IMMUNONUTRITION ON VIRULENCE STRATEGIES IN BACTERIA", Nutrition, 14(7-8), 1998, pp. 580-584

Abstract

A coevolutionary balance exists between bacteria within the mammaliangastrointestinal tract and the lining epithelia. Recent advances in the molecular detection of bacteria have demonstrated that under normalcircumstances, the lining mucosal epithelium in the gastrointestinal tract is sterile. Under conditions of stress and dietary alteration however, the probability of bacteria adhering to and altering epithelialfunction is a reflection of the virulence tactics of the resident bacteria balanced against the innate mucosal defense system. This pathologic event may be caused in part by the adaptive response of intestinalbacteria to their changing environment and food supply. Accustomed toa warm climate and a constant and predictable food supply, bacteria exposed to luminal nutrient starvation and a catabolically stressed host may express virulence determinants that can harm the host. The causes and consequences-of bacterial adherence to host intestinal epitheliaduring stress and dietary manipulation are discussed. Nutrition 1998:14:580-584. (C) Elsevier Science Inc. 1998.

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Documento generato il 19/01/20 alle ore 20:58:46