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Titolo:
ENVIRONMENTAL ASSESSMENT OF DERMATOPHAGOIDES MITE-ALLERGEN LEVELS IN SWEDEN SHOULD INCLUDE DER-M-1
Autore:
WARNER A; BOSTROM S; MUNIR AKM; MOLLER C; SCHOU C; KJELLMAN NIM;
Indirizzi:
HELSINGBORG HOSP,DEPT PAEDIAT S-25187 HELSINGBORG SWEDEN SWEDISH MUSEUM NAT HIST S-10405 STOCKHOLM SWEDEN UNIV UMEA HOSP,DEPT PAEDIAT S-90185 UMEA SWEDEN LINKOPING UNIV,DEPT PAEDIAT LINKOPING SWEDEN ALLERGOLOG LAB HORSHOLM DENMARK
Titolo Testata:
Allergy
fascicolo: 7, volume: 53, anno: 1998,
pagine: 698 - 704
SICI:
0105-4538(1998)53:7<698:EAODML>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
HOUSE-DUST MITE; DER-P-I; ASTHMATIC-CHILDREN; INDOOR ALLERGENS; D-FARINAE; D-PTERONYSSINUS; MAJOR ALLERGEN; D-MICROCERAS; EXPOSURE; SENSITIZATION;
Keywords:
ASTHMA; HOUSE-DUST MITES; IGE ANTIBODIES; MONOCLONAL ANTIBODIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
A. Warner et al., "ENVIRONMENTAL ASSESSMENT OF DERMATOPHAGOIDES MITE-ALLERGEN LEVELS IN SWEDEN SHOULD INCLUDE DER-M-1", Allergy, 53(7), 1998, pp. 698-704

Abstract

The major allergen of Dermatophagoides microceras, Der m 1, as well as the allergens of D. pteronyssinus and D. farinae, Der p 1 and Der f 1, were analyzed in the homes of 111 asthmatic children in three climatic regions in Sweden. The numbers and species of mites were determined by microscopy, and circulating IgE antibodies against mites were measured. Der fl was the predominant house-dust-mite (HDM) allergen, Der p 1 the least often found, and Der m 1 represented 31% of the allergenload. However, in the Linkoping area, Der m 1 was the major HDM allergen (58%). Mite counts and allergen levels correlated well. Current exposure to HDM allergens at home was associated with the serum IgE antibody response to HDM in the children with no threshold level. Of the children with IgE antibodies against HDM, 67% reacted to all three mites. Mite sensitization rates were marginally increased (7%) by the addition of IgE analysis of D, microceras to the routine analysis of IgE antibodies against D, pteronyssinus and D. farinae. Thus, Der m 1 may be an important HDM allergen and should be considered when HDM exposuredata are assessed in areas with a climate like that of Sweden.

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Documento generato il 25/11/20 alle ore 18:13:45