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Titolo:
RELATION BETWEEN THE KINETICS OF TL-201 IN MYOCARDIAL SCINTIGRAPHY AND MYOCARDIAL-METABOLISM IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION
Autore:
YAMAGISHI H; AKIOKA K; TAKAGI M; TANAKA A; TAKEUCHI K; YOSHIKAWA J; OCHI H;
Indirizzi:
OSAKA CITY UNIV,SCH MED,DEPT INTERNAL MED 1,ABENO KU,1-5-7 ASAHI MACHI OSAKA 545 JAPAN OSAKA CITY UNIV,SCH MED,DIV NUCL MED OSAKA JAPAN
Titolo Testata:
HEART
fascicolo: 1, volume: 80, anno: 1998,
pagine: 28 - 34
SICI:
1355-6037(1998)80:1<28:RBTKOT>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRANCHED FATTY-ACIDS; REVERSE REDISTRIBUTION; VIABLE MYOCARDIUM; CORONARY-ARTERY; CLINICAL-SIGNIFICANCE; COMPUTED-TOMOGRAPHY; TL-201 REINJECTION; N-13 AMMONIA; DIFFERENTIATION; REVERSIBILITY;
Keywords:
TL-201 SPECT; BMIPP SPECT; FDG PET; MYOCARDIAL INFARCTION; REDISTRIBUTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
H. Yamagishi et al., "RELATION BETWEEN THE KINETICS OF TL-201 IN MYOCARDIAL SCINTIGRAPHY AND MYOCARDIAL-METABOLISM IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION", HEART, 80(1), 1998, pp. 28-34

Abstract

Objective-To investigate the relations between myocardial metabolism and the kinetics of thallium-201 in myocardial scintigraphy. Methods-46 patients within six weeks after the onset of acute myocardial infarction underwent resting myocardial dual isotope, single acquisition, single photon emission computed tomography (SPECT) using radioiodinated 15-iodophenyl 3-methyl pentadecaenoic acid (BMIPP) and thallium-201, exercise thallium-201 SPECT, and positron emission tomography (PET) using nitrogen-13 ammonia (NH3) and [F18]fluorodeoxyglucose (FDG) under fasting conditions. The left ventricle was divided into nine segments, and the severity of defects was assessed visually. Results-In the resting SPECT, less BMIPP uptake than thallium-201 uptake was observed in all of 40 segments with reverse redistribution of thallium-201, and in21 of 88 segments with a fixed defect of thallium-201 (p < 0.0001); and more FDG uptake than NH, uptake (NH3-FDG mismatch) was observed in 35 of 40 segments with reverse redistribution and in 38 of 88 segmentswith fixed defect (p < 0.0001). Less BMIPP uptake in the resting SPECT was observed in 49 of 54 segments with slow stress redistribution inexercise SPECT, and in nine of 17 segments with rapid stress redistribution (p < 0.0005);NH3-FDG mismatch was observed in 42 of 54 segmentswith slow stress redistribution and in five of 17 segments with rapidstress redistribution (p < 0.0005). Conclusions-Thallium-201 myocardial scintigraphy provides information about not only myocardial perfusion and viability but also about myocardial metabolism in patients withacute myocardial infarction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:20:06