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Titolo:
GROWTH AND DEVELOPMENT OF TERM CHILDREN BORN WITH LOW-BIRTH-WEIGHT - EFFECTS OF GENETIC AND ENVIRONMENTAL-FACTORS
Autore:
STRAUSS RS; DIETZ WH;
Indirizzi:
UNIV MED & DENT NEW JERSEY,ROBERT WOOD JOHNSON MED SCH,DIV PEDIAT GASTROENTEROL & NUTR NEW BRUNSWICK NJ 08903 TUFTS UNIV NEW ENGLAND MED CTR,FLOATING HOSP CHILDREN,DIV PEDIAT GASTROENTEROL & NUTR BOSTON MA 02111 TUFTS UNIV,SCH MED BOSTON MA 02111
Titolo Testata:
The Journal of pediatrics
fascicolo: 1, volume: 133, anno: 1998,
pagine: 67 - 72
SICI:
0022-3476(1998)133:1<67:GADOTC>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOR-GESTATIONAL-AGE; FETAL GROWTH; NUTRITIONAL-STATUS; POSTNATAL-GROWTH; RETARDATION; MORBIDITY; INFANTS; TWINS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
R.S. Strauss e W.H. Dietz, "GROWTH AND DEVELOPMENT OF TERM CHILDREN BORN WITH LOW-BIRTH-WEIGHT - EFFECTS OF GENETIC AND ENVIRONMENTAL-FACTORS", The Journal of pediatrics, 133(1), 1998, pp. 67-72

Abstract

Objective: To evaluate the role of intrauterine growth retardation (IUGR) on childhood growth and development, controlling for environmental and genetic factors. Methods: Women and infants enrolled in the National Collaborative Perinatal Project were analyzed. Weight, length, and IQ were assessed at birth and at 7 years in the entire National Collaborative Perinatal Project population in term infants born with and without IUGR (''population cohort''). To control for genetic and environmental factors, growth and development were also compared in 220 similar-sex term sibling pairs in which one sibling was born with IUGR andone was born without IUGR (''sibling cohort''). Results: At 7 years of age heights and weights of infants born with IUGR remained similar to 0.5 SD less than infants born without IUGR (weight-for-age: p < 0.001, height-for-age: p < 0.001). In the entire National Collaborative Perinatal Project population, IQ (p < 0.001) and Bender-Gestalt (p < 0.001) scores were significantly lower in infants born with IUGR comparedwith those in infants born without IUGR. There were no significant differences in IQ or Bender-Gestalt scores between siblings born with and without IUGR. However, siblings with IUGR and large deficits in headcircumference demonstrated both decreased IQ (p < 0.05) and Bender-Gestalt (p < 0.05) scores. Conclusion: Long-term growth deficits associated with IUGR appear largely independent of prenatal or postnatal environmental factors. IUGR had little impact on intelligence and motor development except when associated with large deficits in head circumference.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 07:49:48