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Titolo:
INCREASED CARBON-MONOXIDE IN EXHALED AIR OF SUBJECTS WITH UPPER RESPIRATORY-TRACT INFECTIONS
Autore:
YAMAYA M; SEKIZAWA K; ISHIZUKA S; MONMA M; MIZUTA K; SASAKI H;
Indirizzi:
TOHOKU UNIV,SCH MED,DEPT GERIATR MED,AOBA KU,SEIRYO MACHI 1-1 SENDAI MIYAGI 980 JAPAN TOHOKU UNIV,SCH MED,DEPT GERIATR MED,AOBA KU SENDAI MIYAGI 980 JAPAN SENDAI NATL HOSP,DIV CLIN RES,VIRUS CTR SENDAI MIYAGI JAPAN
Titolo Testata:
American journal of respiratory and critical care medicine
fascicolo: 1, volume: 158, anno: 1998,
pagine: 311 - 314
SICI:
1073-449X(1998)158:1<311:ICIEAO>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEME OXYGENASE; NITRIC-OXIDE; RAT; GLUCOCORTICOIDS; ACTIVATION; INDUCTION; GENE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
M. Yamaya et al., "INCREASED CARBON-MONOXIDE IN EXHALED AIR OF SUBJECTS WITH UPPER RESPIRATORY-TRACT INFECTIONS", American journal of respiratory and critical care medicine, 158(1), 1998, pp. 311-314

Abstract

Viral infection may induce the expression of heme oxygenase, resulting in increased carbon monoxide (CO) formation. CO may be produced by various cells of the upper and tower respiratory tract and may be detected in the exhaled air. Therefore, exhaled CO concentrations were measured on a CO monitor by vital capacity maneuver in subjects with upperrespiratory tract infections (URTIs) and in nonsmoking and smoking healthy control subjects. At the time of symptoms of URTI, exhaled CO concentrations were 5.6 +/- 0.4 ppm and decreased to 1.0 +/- 0.1 ppm during recovery. Recovery values of exhaled CO were similar to those in age-matched nonsmoking healthy control subjects (1.2 +/- 0.3 ppm). Smoking healthy control subjects had the highest levels of exhaled CO concentration among the groups (18.5 +/- 2.5 ppm). These findings suggest that symptomatic URTIs increase the concentration of CO in exhaled air. This may reflect the induction of heme oxygenase that has an antiviral effect in the airways.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/08/20 alle ore 21:03:04