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Titolo:
PARKINSONISM WITH HIV-INFECTION
Autore:
MIRSATTARI SM; POWER C; NATH A;
Indirizzi:
KENTUCKY CLIN,DEPT NEUROL,L445 LEXINGTON KY 40536 UNIV MANITOBA,DEPT INTERNAL MED,NEUROL SECT WINNIPEG MB CANADA UNIV MANITOBA,DEPT MED MICROBIOL WINNIPEG MB CANADA UNIV KENTUCKY,DEPT NEUROL MICROBIOL & IMMUNOL LEXINGTON KY 00000
Titolo Testata:
Movement disorders
fascicolo: 4, volume: 13, anno: 1998,
pagine: 684 - 689
SICI:
0885-3185(1998)13:4<684:PWH>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; AIDS DEMENTIA COMPLEX; IMMUNE-DEFICIENCY-SYNDROME; CEREBROSPINAL-FLUID; NEUROLOGIC MANIFESTATIONS; EXTRAPYRAMIDAL SYMPTOMS; CEREBRAL TOXOPLASMOSIS; MOVEMENT-DISORDERS; BASAL GANGLIA; REACTION-TIME;
Keywords:
HUMAN IMMUNODEFICIENCY VIRUS (HIV); AIDS; MOVEMENT DISORDERS; PARKINSONISM; BASAL GANGLIA; DEMENTIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
S.M. Mirsattari et al., "PARKINSONISM WITH HIV-INFECTION", Movement disorders, 13(4), 1998, pp. 684-689

Abstract

We describe six patients with parkinsonism and another 10 patients with parkinsonian features with human immunodeficiency virus (HIV) infection. In 50% of these patients, the symptoms were precipitated by neuroleptics. Tn the remaining patients, no obvious cause other than HIV infection was identified. Discontinuation of the neuroleptics produced complete recovery in one patient and partial or no response in others. Rapid progression of parkinsonism was noted in two patients, one of whom was treated with high-dose zidovudine (AZT) and benztropine. We conclude that patients with AIDS are at risk of developing an akinetic parkinsonism which may be precipitated by the use of neuroleptics, response to treatment is variable, and parkinsonism may be another primaryHIV-induced syndrome.

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Documento generato il 23/01/20 alle ore 12:23:27