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Titolo:
GLUCOSE EFFECTS ON COGNITION IN ADULTS WITH DOWNS-SYNDROME
Autore:
MANNING CA; HONN VJ; STONE WS; JANE JS; GOLD PE;
Indirizzi:
UNIV VIRGINIA,HLTH SCI CTR,DEPT NEUROL,BOX 394 CHARLOTTESVILLE VA 22908 UNIV VIRGINIA,DEPT PSYCHOL CHARLOTTESVILLE VA 22908
Titolo Testata:
Neuropsychology
fascicolo: 3, volume: 12, anno: 1998,
pagine: 479 - 484
SICI:
0894-4105(1998)12:3<479:GEOCIA>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALZHEIMERS-DISEASE; SENILE DEMENTIA; MEMORY; AGE; ENHANCEMENT; BRAIN; INDIVIDUALS; DECLINE; HUMANS; YOUNG;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
C.A. Manning et al., "GLUCOSE EFFECTS ON COGNITION IN ADULTS WITH DOWNS-SYNDROME", Neuropsychology, 12(3), 1998, pp. 479-484

Abstract

Glucose enhances memory in a variety of individuals, including peoplewith Alzheimer's disease. By 35 years of age, adults with Down's syndrome (DS) develop the characteristic plaques and tangles found in Alzheimer's disease, despite findings indicating that not all older DS individuals meet criteria for dementia. To examine the possibility that glucose enhances memory in adults with DS (mean age = 35 years, range =19-55 years), adults with DS were given a battery of tests specifically designed for individuals with DS in glucose and control conditions. No participant met criteria for dementia, regardless of age. Glucose enhanced performance on tests requiring both long-term memory and auditory processing. In addition, increased age was associated with poorerperformance on the majority of tests in the control condition, indicating that cognitive decline with aging may be more prevalent in DS than previously believed.

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Documento generato il 07/08/20 alle ore 12:15:38