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Titolo:
THE RELATIONSHIP BETWEEN HEPATITIS-C VIRUS AND SCHISTOSOMIASIS - HISTOPATHOLOGIC EVALUATION OF LIVER-BIOPSY SPECIMENS
Autore:
HELAL TEA; DANIAL MF; AHMED HF;
Indirizzi:
AIN SHAMS FAC MED,DEPT PATHOL CAIRO EGYPT ASSUIT FAC MED,DEPT PATHOL ASSIUT EGYPT AL AIN HOSP,DEPT MED AL AIN U ARAB EMIRATES
Titolo Testata:
Human pathology
fascicolo: 7, volume: 29, anno: 1998,
pagine: 743 - 749
SICI:
0046-8177(1998)29:7<743:TRBHVA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC ACTIVE HEPATITIS; EGYPTIAN BLOOD-DONORS; NON-B-HEPATITIS; VIRAL-HEPATITIS; NON-A; POSTTRANSFUSION HEPATITIS; INFECTION; ANTIBODY; EPIDEMIOLOGY; PREVALENCE;
Keywords:
HCV; SCHISTOSOMIASIS; EGYPTIAN PATIENTS; LIVER BIOPSY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
T.E.A. Helal et al., "THE RELATIONSHIP BETWEEN HEPATITIS-C VIRUS AND SCHISTOSOMIASIS - HISTOPATHOLOGIC EVALUATION OF LIVER-BIOPSY SPECIMENS", Human pathology, 29(7), 1998, pp. 743-749

Abstract

The reported high incidence of anti-HCV seropositivity in the Egyptian population seems surprising. Some suggest that schistosomiasis is the responsible factor, either by producing false positivity for HCV antibodies or by predisposing to actual HCV infection in some way. In an attempt to investigate this unclear relationship on a histological level, we performed a thorough semiquantitative morphological study of liver biopsy specimens from 44 anti-HCV-positive Egyptian patients with chronic liver disease. More than half of these patients (23) had serological evidence of schistosomiasis. The results have shown that all 44liver biopsy specimens demonstrated the histopathological features known to be characteristic of chronic HCN hepatitis. Statistical analysis showed no significant difference between the schistosomal and nonschistosomal groups regarding the semiquantitative histological scores ofthese features. This study confirms the presence of definite HCV-induced hepatic pathology in all anti-HCV seropositive cases. More importantly, it shows the lack of enhancement of this pathology in the schistosomal patients. Copyright (C) 1998 by W.B. Saunders Company.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/05/20 alle ore 14:49:59