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Titolo:
EFFECTS OF LONG-TERM INTRARENAL ANGIOTENSIN-II INFUSION ON RENAL VASCULAR RESPONSIVENESS TO VASOACTIVE AGENTS
Autore:
FITZGERALD SM; STEVENSON KM; EVANS RG; ANDERSON WP;
Indirizzi:
MONASH UNIV,DEPT PHYSIOL CLAYTON VIC 3168 AUSTRALIA MONASH UNIV,DEPT PHYSIOL CLAYTON VIC 3168 AUSTRALIA BAKER MED RES INST,EMILY EE STEWART RENAL LAB MELBOURNE VIC AUSTRALIA
Titolo Testata:
Clinical and experimental pharmacology and physiology
fascicolo: 7-8, volume: 25, anno: 1998,
pagine: 633 - 636
SICI:
0305-1870(1998)25:7-8<633:EOLIAI>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT-KIDNEY; HYPERTENSION; RESPONSES;
Keywords:
ACETYLCHOLINE; ANGIOTENSIN II; DOG; GLYCERYL TRINITRATE; HYPERTENSION; NORADRENALINE; RENAL BLOOD FLOW; RENAL VASCULAR HYPERTROPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
S.M. Fitzgerald et al., "EFFECTS OF LONG-TERM INTRARENAL ANGIOTENSIN-II INFUSION ON RENAL VASCULAR RESPONSIVENESS TO VASOACTIVE AGENTS", Clinical and experimental pharmacology and physiology, 25(7-8), 1998, pp. 633-636

Abstract

1. We tested whether chronic intrarenal angiotensin II (AngII) infusion altered renal vascular responsiveness to vasoactive agents, which would provide evidence of vascular structural changes. 2. The renal blood Bow (RBF) responses to renal arterial administration of bolus dosesof acetylcholine, glyceryl trinitrate, AngII and noradrenaline were measured before commencement of and 1 day after cessation of 28 days intrarenal AngII infusion (0.5 ng/kg per min) in chronically instrumented conscious dogs. 3. The RBF responses to these vasoactive agents wereunaltered by chronic intrarenal AngII infusion in conscious dogs. 4. These functional studies provide no evidence for renal vascular hypertrophy in response to chronic intrarenal AngII infusion in conscious dogs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 13:18:14