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Titolo:
DISSEMINATED CRYPTOCOCCOSIS ASSOCIATED WITH ADRENAL MASSES AND INSUFFICIENCY
Autore:
KAWAMURA M; MIYAZAKI S; MASHIKO S; SUMI M; ASHIDATE K; TOHDA H; HASE K; ANDO N;
Indirizzi:
TOKYO TEISHIN HOSP,DEPT INTERNAL MED,DIV ENDOCRINOL & METAB,CHIYODA KU,2-14-23 FUJIMI TOKYO 102 JAPAN
Titolo Testata:
The American journal of the medical sciences
fascicolo: 1, volume: 316, anno: 1998,
pagine: 60 - 64
SICI:
0002-9629(1998)316:1<60:DCAWAM>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACQUIRED-IMMUNODEFICIENCY-SYNDROME; FINE-NEEDLE ASPIRATION; AMPHOTERICIN-B; MENINGITIS; FLUCONAZOLE; AIDS; FLUCYTOSINE; NEOFORMANS; INFECTION; TRIAL;
Keywords:
CRYPTOCOCCOSIS; PRIMARY ADRENAL INSUFFICIENCY; BILATERAL ADRENAL MASSES; ADRENECTOMY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
M. Kawamura et al., "DISSEMINATED CRYPTOCOCCOSIS ASSOCIATED WITH ADRENAL MASSES AND INSUFFICIENCY", The American journal of the medical sciences, 316(1), 1998, pp. 60-64

Abstract

A case of primary adrenal insufficiency with bilateral adrenal massesand meningitis due to disseminated cryptococcosis in a patient with mild non-insulin-dependent diabetes is presented. The diagnosis was made by fine-needle aspiration biopsy cytology. Although the meningitis responded to antifungal therapy, the bilateral adrenal gland enlargement did not change. Reflecting this, cryptococcal antigen titers became negative in CSF, but fell to 1:8 in serum, Although antifungal therapycontinued, cryptococcal antigen titer increased both in CSF and serumfor 50 days. Because the adrenal glands were the apparent focus for the persistent fungemia, bilateral adrenalectomy was performed, Antifungal therapy for an additional 15 months was needed to achieve negativeserum cryptococcal antigen titers. Although adrenal insufficiency dueto disseminated cryptococcosis is rare in healthy hosts, it should beincluded in differential diagnosis of unilateral and bilateral adrenal masses.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 02:40:29