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Titolo:
SLOWED INFORMATION-PROCESSING IN HIV-1 DISEASE
Autore:
LLORENTE AM; MILLER EN; DELIA LF; SELNES OA; WESCH J; BECKER JT; SATZ P;
Indirizzi:
BAYLOR COLL MED,1 BAYLOR PLAZA HOUSTON TX 77030 UNIV CALIF LOS ANGELES,SCH MED,DEPT PSYCHIAT & BIOBEHAV SCI LOS ANGELES CA 90024 JOHNS HOPKINS UNIV,SCH MED,DEPT NEUROL BALTIMORE MD 21205 HOWARD BROWN HLTH CTR CHICAGO IL 00000 UNIV PITTSBURGH,GRAD SCH PUBL HLTH PITTSBURGH PA 15260
Titolo Testata:
Neuropsychology, development, and cognition. Section A, Journal of clinical and experimental neuropsychology
fascicolo: 1, volume: 20, anno: 1998,
pagine: 60 - 72
SICI:
1380-3395(1998)20:1<60:SIIHD>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTICENTER AIDS COHORT; HUMAN-IMMUNODEFICIENCY-VIRUS; NEUROPSYCHOLOGICAL PERFORMANCE; DEMENTIA COMPLEX; ABNORMALITIES; PREVALENCE; MACS; MEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
A.M. Llorente et al., "SLOWED INFORMATION-PROCESSING IN HIV-1 DISEASE", Neuropsychology, development, and cognition. Section A, Journal of clinical and experimental neuropsychology, 20(1), 1998, pp. 60-72

Abstract

This investigation examined the effects of HIV-1 infection on speededcomplex cognitive processing in a group of HIV-negative (n = 666), HN-positive symptomatic (n = 156), and HIV-positive asymptomatic (n = 623) participants while controlling for the effects of slowed motor functioning, peripheral neuropathy, and several other putative confounds. Stroop Interference and reaction-time tasks served as anchor procedures to assess cognitive processing. The present findings suggest that HIV-1 infection is capable of compromising CNS-mediated cognitive processes (speeded processing) infringing upon their efficacy in the symptomatic stages of the disease while sparing individuals in the asymptomatic stage. The detrimental effects observed on information-processing mechanisms associated with HIV infection persisted despite the use of procedures to control for peripheral nerve integrity and other potential confounds.

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Documento generato il 30/11/20 alle ore 03:21:31