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Titolo:
SCANNING LASER OPHTHALMOSCOPY AS A TOOL FOR DETECTING ATROPHY OF THE CENTRAL RETINAL NERVE-FIBER LAYER IN LEBERS HEREDITARY OPTIC NEUROPATHY
Autore:
LINDBLOM B; BONDTAYLOR L;
Indirizzi:
UNIV GOTEBORG,SAHLGRENS UNIV HOSP,INST CLIN NEUROSCI,DEPT OPHTHALMOL S-41345 GOTHENBURG SWEDEN
Titolo Testata:
Acta ophthalmologica Scandinavica
fascicolo: 3, volume: 76, anno: 1998,
pagine: 356 - 359
SICI:
1395-3907(1998)76:3<356:SLOAAT>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
FIBER LAYER; MUTATIONS;
Keywords:
LEBERS HEREDITARY OPTIC NEUROPATHY; OPTIC ATROPHY; RETINAL NERVE FIBER LAYER; SCANNING LASER OPHTHALMOSCOPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
7
Recensione:
Indirizzi per estratti:
Citazione:
B. Lindblom e L. Bondtaylor, "SCANNING LASER OPHTHALMOSCOPY AS A TOOL FOR DETECTING ATROPHY OF THE CENTRAL RETINAL NERVE-FIBER LAYER IN LEBERS HEREDITARY OPTIC NEUROPATHY", Acta ophthalmologica Scandinavica, 76(3), 1998, pp. 356-359

Abstract

Purpose: To study the central retinal nerve fibre layer with scanninglaser ophthalmoscopy (SLO) in subjects with Leber's hereditary optic neuropathy (LHON), a disease primarily affecting retinal nerve fibres in the macular area. Methods: SLO was performed using combinations of laser wavelengths and aperture settings in subjects with LHON and in age-matched normal controls. Results: Six subjects with LHON were examined. The reduction of central retinal nerve fibre layer was clearly demonstrated on the SLO images. Consistent findings were abnormal visibility and apparent broadening of perifoveal blood vessels. In all six normal controls the temporal nerve fibre raphe could be demonstrated. Conclusions: SLO imaging is an easy way of depicting the central retinal nerve fibre layer, requiring no special photographic skills. The demonstration of nerve fibre reduction is valuable in the early diagnosisof LHON.

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Documento generato il 25/11/20 alle ore 17:49:45