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Titolo:
THE SUICIDE BRAIN - A REVIEW OF POSTMORTEM RECEPTOR TRANSPORTER BINDING-STUDIES/
Autore:
GROSSISSEROFF R; BIEGON A; VOET H; WEIZMAN A;
Indirizzi:
WEIZMANN INST SCI,DEPT MEMBRANE RES & BIOPHYS IL-76100 REHOVOT ISRAEL PHARMOS LTD REHOVOT ISRAEL HEBREW UNIV JERUSALEM,FAC AGR,DEPT AGR ECON IL-76100 REHOVOT ISRAEL TEL AVIV UNIV,SACKLER FAC MED,BEILINSON MED CTR,FELSENSTEIN MED RES CTR,GEHAH PSYCHIAT HOSP IL-69978 TEL AVIV ISRAEL
Titolo Testata:
Neuroscience and biobehavioral reviews
fascicolo: 5, volume: 22, anno: 1998,
pagine: 653 - 661
SICI:
0149-7634(1998)22:5<653:TSB-AR>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADRENERGIC-RECEPTOR BINDING; REGIONALLY SELECTIVE INCREASES; TRITIATED IMIPRAMINE BINDING; FREE DEPRESSED SUICIDES; 5-HT UPTAKE SITES; FRONTAL-CORTEX; AUTORADIOGRAPHIC ANALYSIS; ANTIDEPRESSANT TREATMENT; SEROTONERGIC MEASURES; MAJOR DEPRESSION;
Keywords:
SUICIDE; BRAIN; DEPRESSION; SEROTONIN; NOREPINEPHRINE; OPIOIDS; GABA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
75
Recensione:
Indirizzi per estratti:
Citazione:
R. Grossisseroff et al., "THE SUICIDE BRAIN - A REVIEW OF POSTMORTEM RECEPTOR TRANSPORTER BINDING-STUDIES/", Neuroscience and biobehavioral reviews, 22(5), 1998, pp. 653-661

Abstract

The present review summarizes the last 15 years of research involvingpostmortem receptor/transporter binding studies on brains of suicide victims. It is our working hypothesis, on the basis of psychological, behavioral and epidemiological studies, that suicidal behavior is an independent unique behavioral entity with specific neurochemical characteristics. This review tries to test this hypothesis at the level of neurotransmitter receptors by using a different approach to data analysis. We suggest that this statistical approach, involving multivariate analyses, can contribute to the formulation of new hypotheses at the level of molecular biology and genetics. Such studies if undertaken in the future, would help define suicidal behavior as a psycho-neuro-pathological entity. (C) 1998 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 09:17:54