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Titolo:
FRACTAL ANALYSIS - A NEW APPROACH IN BRAIN RECEPTOR IMAGING
Autore:
KUIKKA J; TIIHONEN J;
Indirizzi:
KUOPIO UNIV HOSP,DEPT CLIN PHYSIOL,POB 1777 FIN-70211 KUOPIO FINLAND UNIV KUOPIO,DEPT FORENS PSYCHIAT FIN-70211 KUOPIO FINLAND
Titolo Testata:
Annals of medicine
fascicolo: 3, volume: 30, anno: 1998,
pagine: 242 - 248
SICI:
0785-3890(1998)30:3<242:FA-ANA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; NAIVE SCHIZOPHRENIC-PATIENTS; D2 DOPAMINE-RECEPTORS; PANIC DISORDER; STRIATAL D-2; IN-VIVO; BINDING; ADVANTAGE; ALCOHOL;
Keywords:
BRAIN; FRACTALS; POSITRON EMISSION TOMOGRAPHY; RECEPTOR; SINGLE-PHOTON EMISSION TOMOGRAPHY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
45
Recensione:
Indirizzi per estratti:
Citazione:
J. Kuikka e J. Tiihonen, "FRACTAL ANALYSIS - A NEW APPROACH IN BRAIN RECEPTOR IMAGING", Annals of medicine, 30(3), 1998, pp. 242-248

Abstract

Improvements in detector technology and the development of radioligands for brain receptor imaging have introduced exiting new insights into the pathophysiology of various neuropsychiatric disorders and have improved the possibilities of optimizing the treatment for patients suffering from them. Positron emission tomography (PET) and single-photonemission tomography (SPET) with tailored radiopharmaceuticals provideinformation on the topographic physiological chemistry of the living human brain. The different patterns of brain receptor densities and distribution can be imaged and modelled with PET and SPET. The normal receptor distribution in the brain is broadly heterogeneous with different cortical layers, which show receptor densities varying from very low to high. Further exploration of the data shows that human neurophysiology and neural architectures possess fractal properties that may be altered during activation and in different neuropsychiatric disorders. This review highlights recent findings in SPET receptor imaging and the use of fractal analysis in the interpretation of images representing various neuropsychiatric disorders.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 19:11:05