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Titolo:
RISPERIDONE VERSUS HALOPERIDOL FOR PERCEPTION OF EMOTION IN TREATMENT-RESISTANT SCHIZOPHRENIA - PRELIMINARY FINDINGS
Autore:
KEE KS; KERN RS; MARSHALL BD; GREEN MF;
Indirizzi:
W LOS ANGELES VET AFFAIRS MED CTR,11301 WILSHIRE BLVD,116AR,BLDG 208 LOS ANGELES CA 90073 UNIV CALIF LOS ANGELES,DEPT PSYCHOL LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,DEPT PSYCHIAT & BIOBEHAV SCI LOS ANGELES CA 90024 CAMARILLO STATE HOSP & DEV CTR CAMARILLO CA 00000
Titolo Testata:
Schizophrenia research
fascicolo: 2-3, volume: 31, anno: 1998,
pagine: 159 - 165
SICI:
0920-9964(1998)31:2-3<159:RVHFPO>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENERALIZED POOR PERFORMANCE; SOCIAL SKILL; RECOGNITION; DISORDERS;
Keywords:
RISPERIDONE; HALOPERIDOL; EMOTION PERCEPTION; SCHIZOPHRENIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
K.S. Kee et al., "RISPERIDONE VERSUS HALOPERIDOL FOR PERCEPTION OF EMOTION IN TREATMENT-RESISTANT SCHIZOPHRENIA - PRELIMINARY FINDINGS", Schizophrenia research, 31(2-3), 1998, pp. 159-165

Abstract

Currently, little is known about the pharmacological effects of the new generation of antipsychotic medications on perception of emotion inschizophrenia. The present study was designed to compare the effects of risperidone versus haloperidol on the ability to perceive emotion in 20 treatment-resistant schizophrenia patients, using a double-blind design. Measures of emotion perception included a facial emotion identification test (still photographs presented on videotape), a voice emotion identification test (audiotape), and an affect perception lest (brief interpersonal vignettes presented on videotape). These measures were administered during the final week of baseline and after 8 weeks of double-blind medication. Risperidone treatment produced a greater effect cn patients' ability to perceive emotion compared with haloperidol treatment. Additionally, all patients who received risperidone demonstrated improvement in performance between baseline and retest, compared with four of the nine patients who received haloperidol. When changes in positive symptoms were statistically controlled, the results remained significant. These findings suggest that risperidone may facilitate patients' ability to accurately perceive emotion, an effect which may be mediated either directly by risperidone's pharmacological action or perhaps indirectly by its influence on basic neurocognition. (C) 1998 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 10:58:17