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Titolo:
RELATIONSHIP OF AGE, AGE AT ONSET, AND SEX TO DEPRESSION IN OLDER ADULTS
Autore:
LAVRETSKY H; LESSER IM; WOHL M; MILLER BL;
Indirizzi:
UNIV CALIF LOS ANGELES,INST NEUROPSYCHIAT,760 WESTWOOD PLAZA LOS ANGELES CA 90024 HARBOR UCLA MED CTR,DEPT PSYCHIAT TORRANCE CA 90509 HARBOR UCLA MED CTR,DEPT NEUROL TORRANCE CA 90509
Titolo Testata:
The American journal of geriatric psychiatry
fascicolo: 3, volume: 6, anno: 1998,
pagine: 248 - 256
SICI:
1064-7481(1998)6:3<248:ROAAAO>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
GERIATRIC DEPRESSION; LATE-LIFE; SUBCORTICAL HYPERINTENSITIES; SIGNAL HYPERINTENSITIES; REVERSIBLE DEMENTIA; MAJOR DEPRESSION; RISK-FACTORS; SYMPTOMS; GENDER; EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Citazioni:
62
Recensione:
Indirizzi per estratti:
Citazione:
H. Lavretsky et al., "RELATIONSHIP OF AGE, AGE AT ONSET, AND SEX TO DEPRESSION IN OLDER ADULTS", The American journal of geriatric psychiatry, 6(3), 1998, pp. 248-256

Abstract

The authors investigated the relationships among factors of age, age at onset, and sex in depressed older adults. A group of 96 outpatients(mean age, 60) diagnosed with late(LOD) and early-onset (EOD) major depression were assessed for severity of depression and underwent magnetic resonance imaging (MRI). The MRI scans were rated for severity of white-matter hyperintensities (WMH) and ventricle-to-brain ratio (VBR). LOD was associated with increased amounts of WMH, larger VBR, and history of hypertension. Men were more severely depressed than women, with higher rates of neurovegetative signs and history of smoking. Age correlated with increased VBR and WMH, history of hypertension, historyof precipitants for the current episode, and lack of social support. Results suggest that a subgroup of melt may be more at risk for LOD associated with WMH and that sex and age at onset need to be considered in future studies.

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Documento generato il 02/04/20 alle ore 08:22:06