Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
PET IMAGING STUDIES IN DRUG-ABUSE
Autore:
FOWLER JS; VOLKOW ND;
Indirizzi:
BROOKHAVEN NATL LAB,DEPT CHEM UPTON NY 11973 SUNY STONY BROOK STONY BROOK NY 11794
Titolo Testata:
Journal of toxicology. Clinical toxicology
fascicolo: 3, volume: 36, anno: 1998,
pagine: 163 - 174
SICI:
0731-3810(1998)36:3<163:PISID>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; BRAIN GLUCOSE-METABOLISM; CEREBRAL BLOOD-FLOW; PLATELET MONOAMINE-OXIDASE; CIGARETTE SMOKERS; DOPAMINE TRANSPORTER; ALCOHOL-INTOXICATION; COCAINE ABUSERS; BABOON BRAIN; INHIBITION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
77
Recensione:
Indirizzi per estratti:
Citazione:
J.S. Fowler e N.D. Volkow, "PET IMAGING STUDIES IN DRUG-ABUSE", Journal of toxicology. Clinical toxicology, 36(3), 1998, pp. 163-174

Abstract

In spite of the massive public health problem associated with drug abuse, effective treatments remain elusive. This is due in part to a relatively poor understanding of the neurochemical changes which drugs ofabuse produce in the human brain and the relationship of these changes to the behavioral and addictive properties of drugs. With the development of modern imaging methods and a variety of labeled drugs and radiotracers, it has now become possible to track many aspects of drug pharmacokinetics and pharmacodynamics directly in the human brain and torelate these parameters to the behavioral and toxic properties of drugs. Review: In this article, we will highlight some examples of the use of Positron Emission Tomography to measure drug pharmacokinetics andpharmacodynamics and their relationship to addiction and to toxicity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 06:30:22