Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
LONG-TERM RESULTS OF COBALT-60 PLAQUE RAD IOTHERAPY IN THE TREATMENT OF UVEAL MELANOMAS
Autore:
BACIN F; KWIATKOWSKI F; DALENS H; ROZAN R; GAGYI S; DONNARIEIX D; BARD JJ; ROBERT JL;
Indirizzi:
CHRU,HOP GABRIEL MONTPIED,CLIN OPHTALMOL,BP 69 F-63003 CLERMONT FERRAFRANCE
Titolo Testata:
Journal francais d'ophtalmologie
fascicolo: 5, volume: 21, anno: 1998,
pagine: 333 - 344
SICI:
0181-5512(1998)21:5<333:LROCPR>2.0.ZU;2-3
Fonte:
ISI
Lingua:
FRE
Soggetto:
MALIGNANT-MELANOMA; CHOROIDAL MELANOMA; THERAPY; ENUCLEATION; COMPLICATIONS; RECURRENCE; SURVIVAL;
Keywords:
COBALT 60; COMPLICATIONS; PLAQUE RADIOTHERAPY; UVEAL MELANOMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
F. Bacin et al., "LONG-TERM RESULTS OF COBALT-60 PLAQUE RAD IOTHERAPY IN THE TREATMENT OF UVEAL MELANOMAS", Journal francais d'ophtalmologie, 21(5), 1998, pp. 333-344

Abstract

Purpose To analyze 65 patients with uveal melanomas treated with cobalt plaque therapy with regards to mortality, visual results and complications. Patients and methods Most of the melanomas were large (T3: 52.5 %), with a mean largest dimension of the base of 11 mm, and a mean thickness of 6 mm. Most of the tumors were located in the choroid (95 %), with an anterior margin behind the equator (64 %), and a posteriormargin at less than 3 mm of the disc and/or of the macula (69 %). Theplaque radiotherapy delivered a mean dose of 95 Gy to the tumor apex,either with a cobalt plaque alone (51 cases), or in association with a ruthenium plaque (14 cases). The mean follow up period was over 8 years. Results The local control was achieved initially in 86 % of the eyes. The estimated melanoma specific survival rate was 83 % after 5 years and 74 % after 10 years. The main parameter associated with the metastases was the largest dimension of the base (p < 0.01). The eye wasretained in 83 % of the cases. The probability of keeping a vision better than or equal to 0,1 was 39 % after 5 years and 27 % after 10 years. The main parameter associated with the visual loss was the tumor size (p < 0.01). The complications included cataract (39 %), radiation retinopathy (34 %), with maculopathy (19 %) and/or papillopathy (13.5 %), vitreous hemorrhages (22 %), neovascular glaucoma (15 %) and retinal detachment (12 %). Conclusion These results supported the value of cobalt plaque radiotherapy in the management of uveal melanomas.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 06:19:03