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Titolo:
QUANTIFICATION OF EXERCISE-INDUCED PULMONARY HEMORRHAGE WITH BRONCHOALVEOLAR LAVAGE
Autore:
MEYER TS; FEDDE MR; GAUGHAN EM; LANGSETMO I; ERICKSON HH;
Indirizzi:
KANSAS STATE UNIV,COLL VET MED,DEPT ANAT & PHYSIOL MANHATTAN KS 66506 KANSAS STATE UNIV,COLL VET MED,DEPT ANAT & PHYSIOL MANHATTAN KS 66506 KANSAS STATE UNIV,COLL VET MED,DEPT CLIN SCI MANHATTAN KS 66506
Titolo Testata:
Equine veterinary journal
fascicolo: 4, volume: 30, anno: 1998,
pagine: 284 - 288
SICI:
0425-1644(1998)30:4<284:QOEPHW>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
HORSES; HEMORRHAGE; DISEASE; THOROUGHBREDS; CAPILLARIES; RACEHORSES; CYTOLOGY; VOLUME;
Keywords:
HORSE; EXERCISE-INDUCED PULMONARY HEMORRHAGE; BRONCHOALVEOLAR LAVAGE; EXERCISE; HAEMOSIDEROPHAGES; PULMONARY ARTERY PRESSURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
T.S. Meyer et al., "QUANTIFICATION OF EXERCISE-INDUCED PULMONARY HEMORRHAGE WITH BRONCHOALVEOLAR LAVAGE", Equine veterinary journal, 30(4), 1998, pp. 284-288

Abstract

Exercise-induced pulmonary haemorrhage (EIPH) causes serious economiclosses in the horse racing industry. Endoscopic examination indicatesthat 40-90% of horses exhibit EIPH following sprint exercise, but thelimitations of the endoscope prevent diagnosis in many horses. Bronchoalveolar lavage (BAL) was utilised to detect red blood cells (RBCs) in the terminal airways in 6 horses. Two lavages were performed at weekly intervals prior to exercise, one within 90 min after exercise, and 5 at weekly intervals after exercise. The horses were exercised strenuously at 12.5-14.6 mis on a treadmill (3 degree incline). Heart rates ranged from 192-207 beats/min, and mean pulmonary arterial pressures (mPAP) ranged from 80-102 mmHg. Neither epistaxis nor endoscopic evidence of EIPH was seen in any of the 6 horses following exercise. Howeverthe number of RBCs in the lavage fluid increased significantly over control values immediately after exercise in all horses but returned tocontrol values by one week after exercise. Haemosiderophages in the BAL fluid did not increase until one week after exercise and remained elevated for 3 weeks after exercise. Twenty per cent of the total population of alveolar macrophages contained haemosiderin. A positive relationship occurred between the number of RBCs in the lavage fluid and mPAP; the amount of haemorrhage increased as the mPAP exceeded 80 to 90 mmHg. The results with BAL used as the diagnostic tool, suggest that all strenuously exercised horses may exhibit EIPH; the amount of haemorrhage appears to be associated with the magnitude of the high pulmonary arterial pressure.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 21:10:28