Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
NEUROPSYCHOLOGICAL RESULTS OF CRANIOPHARYNGIOMA SURGERY IN ADULTS - APROSPECTIVE-STUDY
Autore:
HONEGGER J; BAROCKA A; SADRI B; FAHLBUSCH R;
Indirizzi:
UNIV ERLANGEN NURNBERG,DEPT NEUROSURG,KOPFKLINIKUM,SCHWABACHANLAGE 6 D-91054 ERLANGEN GERMANY UNIV ERLANGEN NURNBERG,DEPT PSYCHIAT D-91054 ERLANGEN GERMANY
Titolo Testata:
Surgical neurology
fascicolo: 1, volume: 50, anno: 1998,
pagine: 19 - 28
SICI:
0090-3019(1998)50:1<19:NROCSI>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
FRONTAL-LOBE LESIONS; CHILDHOOD CRANIOPHARYNGIOMA; SURGICAL-MANAGEMENT; RADIATION-THERAPY; RADICAL EXCISION; CHILDREN; RADIOTHERAPY; IRRADIATION;
Keywords:
CRANIOPHARYNGIOMA; SURGERY; NEUROPSYCHOLOGY; QUALITY OF LIFE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
J. Honegger et al., "NEUROPSYCHOLOGICAL RESULTS OF CRANIOPHARYNGIOMA SURGERY IN ADULTS - APROSPECTIVE-STUDY", Surgical neurology, 50(1), 1998, pp. 19-28

Abstract

BACKGROUND. The optimal management of craniopharyngiomas is a topic of ongoing debate. Supporters of limited surgery for craniopharyngiomasclaim that more radical approaches are afflicted with adverse neuropsychological sequelae. Since prospective studies on this issue have notyet been performed, we assessed neuropsychological functioning in adults before and after craniopharyngioma surgery. METHODS. Thirteen adults with an age range of 17-76 years (mean, 45 years) were included in the study. Surgery included a transcranial procedure in 10 patients. The bifrontal interhemispheric approach predominated (n = 7). Neuropsychological evaluation was performed before and 3 months after surgery. The test battery was adjusted to evaluate function related to structures in the operative trajectory and at the tumor site. RESULTS. A complete tumor removal was accomplished in eight patients and subtotal removal in three patients. IQ scores for verbal intelligence were in the normal range and not affected by surgery (mean IQ score preoperative: 106.8; postoperative 107.4). In 12 of 13 patients, immediate recall, delayed recall and recognition memory were not impaired after surgery. Postoperative results for abstract thinking were in the normal or above-normal range. Cognitive speed was impaired in three patients preoperatively and in two patients postoperatively. Overall results were significantly better after surgery. Word fluency was not affected by surgery. Quality of life for the category ''sleep'' was impaired preoperatively, and this improved after surgery. Otherwise, quality of life was normal both before and after surgery. CONCLUSIONS. Neuropsychological performance and quality of life are generally not impaired after surgical removal of craniopharyngiomas. The findings support the attitude that the initial therapy of craniopharyngiomas should be an attempt at total removal. (C) 1998 by Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 20:37:11