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Titolo:
EFFECT OF PREOPERATIVE INFLAMMATION OF THE WOUND BED ON SURVIVAL OF SKIN FLAPS IN RATS
Autore:
SKOLLEBORG KC; SAMDAL F;
Indirizzi:
NATL HOSP NORWAY,DEPT PLAST SURG N-0027 OSLO NORWAY UNIV BERGEN,SURG RES LAB N-5014 BERGEN NORWAY
Titolo Testata:
Scandinavian journal of plastic and reconstructive surgery and hand surgery
fascicolo: 3, volume: 27, anno: 1993,
pagine: 167 - 171
SICI:
0284-4311(1993)27:3<167:EOPIOT>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIAC-OUTPUT; MICROSPHERE-METHOD; ANGIOGENESIS; NEOVASCULARIZATION; MACROPHAGES; NECROSIS; GROWTH; PROSTAGLANDINS; CHLORPROMAZINE; ALLOPURINOL;
Keywords:
SKIN FLAP SURVIVAL; INFLAMMATION; ANGIOGENESIS; MICROSPHERE METHOD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
K.C. Skolleborg e F. Samdal, "EFFECT OF PREOPERATIVE INFLAMMATION OF THE WOUND BED ON SURVIVAL OF SKIN FLAPS IN RATS", Scandinavian journal of plastic and reconstructive surgery and hand surgery, 27(3), 1993, pp. 167-171

Abstract

Pedicled dorsal flaps were raised and resutured on the backs of 20 rats. Aseptic inflammation of the bed of the wound flap was induced one week before the operation in 10 rats by scratching with a needle; the other 10 acted as controls. A week after the operation the extent of necrosis was estimated by computer assisted planimetry. Blood flow in the four quarters of the flap and in normal skin was estimated using the microsphere technique. A larger mean area of the skin flaps survivedin rats in which the wound bed had been scratched (71%) compared withthe controls (61%) (p < 0.05); blood flow in the flaps was also higher (p < 0.0005). We conclude that the most likely explanation for theseresults was preoperative angiogenesis in the wound bed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:53:14