Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
IN-VIVO EFFECTS OF HEPATOCYTE GROWTH-FACTOR SCATTER FACTOR ON MOUSE MAMMARY-GLAND DEVELOPMENT
Autore:
YANT J; BULUWELA L; NIRANJAN B; GUSTERSON B; KAMALATI T;
Indirizzi:
INST CANC RES,SECT CELL BIOL & EXPT PATHOL,15 COTSWOLD RD SUTTON SM2 5NG SURREY ENGLAND INST CANC RES,SECT CELL BIOL & EXPT PATHOL SUTTON SM2 5NG SURREY ENGLAND CHARING CROSS & WESTMINSTER MED SCH,DEPT BIOCHEM & MED ONCOL LONDON W6 8RF ENGLAND
Titolo Testata:
Experimental cell research
fascicolo: 2, volume: 241, anno: 1998,
pagine: 476 - 481
SICI:
0014-4827(1998)241:2<476:IEOHGS>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
C-MET; MORPHOGENESIS; MESENCHYME; RECEPTOR; EMBRYO; CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
J. Yant et al., "IN-VIVO EFFECTS OF HEPATOCYTE GROWTH-FACTOR SCATTER FACTOR ON MOUSE MAMMARY-GLAND DEVELOPMENT", Experimental cell research, 241(2), 1998, pp. 476-481

Abstract

We have recently demonstrated the regulated expression of HGF/SF and its receptor (c-met) during mouse mammary gland development together with the mitogenic, motogenic and morphogenic effects of exogenous HGF/SF on primary mammary epithelial cells in culture. This study was undertaken to analyze the influence of HGF/SF on reconstituted mouse mammary gland development in vivo. Here we report that overexpression of HGF/SF induces a range of alterations in the architecture of virgin mouse mammary gland. These include an enhancement of ductal end bud (mammary gland morphoregulatory control point) size and numbers and hyperplastic branching morphogenesis. These data are the first demonstration of the effects of HGF/SF on mammary epithelium in vivo. (C) 1998 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 10:12:29