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Titolo:
HIGH PREVALENCE OF CHLAMYDIA-PNEUMONIAE DNA IN PERIPHERAL-BLOOD MONONUCLEAR-CELLS IN PATIENTS WITH CARDIOVASCULAR-DISEASE AND IN MIDDLE-AGED BLOOD-DONORS
Autore:
BOMAN J; SODERBERG S; FORSBERG J; BIRGANDER LS; ALLARD A; PERSSON K; JIDELL E; KUMLIN U; JUTO P; WALDENSTROM A; WADELL G;
Indirizzi:
UMEA UNIV HOSP,DEPT CLIN VIROL S-90185 UMEA SWEDEN UMEA UNIV,DEPT CLIN VIROL UMEA SWEDEN UMEA UNIV,DEPT MED UMEA SWEDEN UMEA UNIV,DEPT TRANSFUS MED UMEA SWEDEN MALMO UNIV HOSP,DEPT CLIN VIROL MALMO SWEDEN
Titolo Testata:
The Journal of infectious diseases
fascicolo: 1, volume: 178, anno: 1998,
pagine: 274 - 277
SICI:
0022-1899(1998)178:1<274:HPOCDI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERY; PCR; ANTIBODIES; TWAR; IGG;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
J. Boman et al., "HIGH PREVALENCE OF CHLAMYDIA-PNEUMONIAE DNA IN PERIPHERAL-BLOOD MONONUCLEAR-CELLS IN PATIENTS WITH CARDIOVASCULAR-DISEASE AND IN MIDDLE-AGED BLOOD-DONORS", The Journal of infectious diseases, 178(1), 1998, pp. 274-277

Abstract

Nested polymerase chain reaction (nPCR) demonstrated the presence of Chlamydia pneumoniae-specific DNA in peripheral blood mononuclear cells (PBMC). PBMC samples were obtained from 103 consecutive patients (62male, 41 female) aged 22-85 years (mean, 64) admitted for coronary angiography because of suspected coronary heart disease and from 52 blood donors (43 male, 9 female) aged 40-64 years (mean, 49). Of the 101 evaluable patients, 60 (59%) were identified by nPCR assay as C. pneumoniae DNA carriers; C. pneumoniae-specific microimmunofluorescence (MIF) serology confirmed exposure to the bacterium in 57 (95%) of the 60 nPCR-positive patients. Among the 52 blood donors, the nPCR assay identified 24 (46%) C. pneumoniae DNA carriers, all of whom were positive by C. pneumoniae-specific serology. Thirty-two patients (32%) and 23 blood donors (44%) were MIF antibody-positive but repeatedly nPCR-negative; Bartonella henselae- or Bartonella quintana-specific antibodies were not detected among any of these subjects. In this study, C. pneumoniae DNA was common in PBMC of patients with coronary heart disease andin middle-a,oed blood donors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:41:00