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Titolo:
ENERGY ECONOMY OF HUMAN UTERINE MUSCLE STRIPS UNDER DIFFERENT IN-VITRO CONDITIONS AND ITS DEPENDENCE ON TISSUE REDOX POTENTIAL
Autore:
WEDENBERG K; RONQUIST G; ULMSTEN U; WALDENSTROM A;
Indirizzi:
UNIV UPPSALA,UNIV HOSP,DEPT CLIN CHEM S-75185 UPPSALA SWEDEN UNIV UPPSALA,UNIV HOSP,DEPT CLIN CHEM S-75185 UPPSALA SWEDEN UNIV UPPSALA,UNIV HOSP,DEPT OBSTET & GYNECOL S-75185 UPPSALA SWEDEN UNIV UPPSALA,UNIV HOSP,DEPT INTERNAL MED S-75185 UPPSALA SWEDEN
Titolo Testata:
European journal of obstetrics, gynecology, and reproductive biology
fascicolo: 1, volume: 62, anno: 1995,
pagine: 115 - 119
SICI:
0301-2115(1995)62:1<115:EEOHUM>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHARGE; CELLS; ATP; STARVATION; RECOVERY; INJURY;
Keywords:
ENERGY CHARGE; ATP; NAD; MYOMETRIUM; UTERUS; HUMAN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
K. Wedenberg et al., "ENERGY ECONOMY OF HUMAN UTERINE MUSCLE STRIPS UNDER DIFFERENT IN-VITRO CONDITIONS AND ITS DEPENDENCE ON TISSUE REDOX POTENTIAL", European journal of obstetrics, gynecology, and reproductive biology, 62(1), 1995, pp. 115-119

Abstract

Objective: To study the energy economy of human myometrium in vitro, Study design: Myometric biopsies were kept for 10 min or 4 h in a buffer solution at +4 degrees C before preparation into 'early' and 'late'strips, respectively. The strips were perifused at +37 degrees C for different periods of time. Adenylates, energy charge (EC), adenosine and NAD(+) were determined in individual strips. Results. Mean EC and ATP values were low, the 'late' strips displaying 5% and 20% lower values than the 'early' strips, respectively. During perifusion the EC increased slightly, ADP decreased significantly and the strips began to contract. A correlation fitting a multiplicative function was evident between EC and NAD(+) (r = 0.89, P < 0.001). Conclusion: Human myometrium, being operative at an unusually low EC level, maintained its energy economizing and contractile functions in vitro for 4 h, displaying atight relationship between EC and NAD(+), suggestive of a compromisedenergy balance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 15:22:57