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Titolo:
INITIALLY UNRESECTABLE HILAR CHOLANGIOCARCINOMA - HEPATIC REGENERATION AFTER TRANSARTERIAL EMBOLIZATION
Autore:
VOGL TJ; BALZER JO; DETTE K; HINTZE R; PEGIOS W; MAURER J; KECK H; NEUHAUS P; FELIX R;
Indirizzi:
HUMBOLDT UNIV,UNIV HOSP CHARITE,DEPT RADIOL,CAMPUS VIRCHOW,AUGUSTENBURGER PL 1 D-13353 BERLIN GERMANY HUMBOLDT UNIV,UNIV HOSP CHARITE,DEPT SURG D-13353 BERLIN GERMANY HUMBOLDT UNIV,UNIV HOSP CHARITE,DEPT GASTROENTEROL D-13353 BERLIN GERMANY
Titolo Testata:
Radiology
fascicolo: 1, volume: 208, anno: 1998,
pagine: 217 - 222
SICI:
0033-8419(1998)208:1<217:IUHC-H>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY HEPATOCELLULAR-CARCINOMA; PORTAL-VEIN EMBOLIZATION; ARTERIAL EMBOLIZATION; RESECTION; HEPATECTOMY; SURGERY;
Keywords:
BILE DUCTS, NEOPLASMS; HEPATIC ARTERIES, THERAPEUTIC BLOCKADE; LIVER, CT; LIVER, REGENERATION; LIVER, SURGERY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
T.J. Vogl et al., "INITIALLY UNRESECTABLE HILAR CHOLANGIOCARCINOMA - HEPATIC REGENERATION AFTER TRANSARTERIAL EMBOLIZATION", Radiology, 208(1), 1998, pp. 217-222

Abstract

PURPOSE: to assess with volumetric computed tomography (CT) the pattern and extent of hepatic regeneration induced with transarterial embolization of initially unresectable hilar cholangiocarcinoma (Klatskin tumor). MATERIALS AND METHODS: In this prospective study, 13 patients (four men, nine women) with hila r cholangiocarcinoma, aged 43-74 years(mean +/- 1 standard deviation, 59.9 years +/- 9.6), underwent preoperative embolization of the right hepatic lobe. Embolization was performed transarterially by using four to 15 embolization coils. volumetricmeasurements of the entire liver, left hepatic lobe, and spleen were performed with contrast material-enhanced and unenhanced helical CT before and after embolization in all patients. RESULTS: After right lobeembolization, volumetric helical CT measurements revealed a 2%-33% decrease (mean, 10%) in the volume of the affected right hepatic lobe, an 11%-68% increaew (mean, 37%) in the volume of left hepatic lobe parenchyma, and variations in splenic volume of -5% to +28% (mean, +11%). Nine patients underwent extended hepatectomy 27-75 days (mean, 44 days) after embolization. No patient had severe complications due to embolization. CONCLUSION: In patients with an initially unresectable bilateral Klatskin tumor, right lobar arterial coil embolization results in enlargement of the left hepatic lobe (as verified with volumetric helical CT), thus allowing right hemihepatectomy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 13:24:18