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Titolo:
BILATERAL LOSS OF VESTIBULAR FUNCTION - CLINICAL FINDINGS IN 53 PATIENTS
Autore:
RINNE T; BRONSTEIN AM; RUDGE P; GRESTY MA; LUXON LM;
Indirizzi:
NATL HOSP NEUROL & NEUROSURG,INST NEUROL,MCR HUMAN MOVEMENT & BALANCEUNIT LONDON WC1N 3BG ENGLAND NATL HOSP NEUROL & NEUROSURG,INST NEUROL,MCR HUMAN MOVEMENT & BALANCEUNIT LONDON WC1N 3BG ENGLAND NATL HOSP NEUROL & NEUROSURG,DEPT NEUROOTOL LONDON WC1N 3BG ENGLAND
Titolo Testata:
Journal of neurology
fascicolo: 6-7, volume: 245, anno: 1998,
pagine: 314 - 321
SICI:
0340-5354(1998)245:6-7<314:BLOVF->2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
BACTERIAL-MENINGITIS; OSCILLOPSIA; NEUROPATHY; FAILURE; HEARING; DISEASE; REFLEX;
Keywords:
VESTIBULAR FAILURE; NEUROLOGICAL DISEASE; OTOLOGICAL DISORDERS; OTOTOXICITY; AUTOIMMUNE DISORDERS; OSCILLOPSIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
T. Rinne et al., "BILATERAL LOSS OF VESTIBULAR FUNCTION - CLINICAL FINDINGS IN 53 PATIENTS", Journal of neurology, 245(6-7), 1998, pp. 314-321

Abstract

The clinical presentations and aetiologies of a series of 53 cases ofbilateral vestibular failure (BVF) seen by the authors over a decade were evaluated by retrospective review of the medical records. Thirty-nine per cent of patients had associated neurological disease; 13% hada progressive cerebellar syndrome with disabling: gait ataxia, abnormal eye movements and cerebellar atrophy on neuro-imaging. BVF was usually unsuspected. Nine per cent had cranial or peripheral neuropathies and in this group there was no abnormality of brain stem/cerebellar oculomotor function, but hearing loss was common. Eleven per cent revealed BVF and hearing loss secondary to meningitis, and 6% had other neurological disorders. Idiopathic BVF was found in 21% of cases, characterised by paroxysmal vertigo and/or oscillopsia, but no abnormal clinical signs. Gentamicin ototoxicity accounted for a further 17%, while autoimmune disease was present in 9% of patients. Otological or neoplastic disease was diagnosed in the remaining 13% of patients. It was concluded that neurological, audiological and ocular motor assessments allow the probable cause of BVF to be defined in approximately 80% of cases. A group of BVF related to autoimmune pathologies is reported for the first time, indicating the need for immunological screening. Idiopathic BVF ma; present with only minor visual or vestibular symptoms, while in patients with cerebellar degeneration, BVF may be unsuspected and, thus, underdiagnosed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 05:25:19