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Titolo:
MOLECULAR AND IMMUNOLOGICAL CHARACTERISTICS OF LATEX ALLERGENS
Autore:
BREITENEDER H; SCHEINER O;
Indirizzi:
UNIV VIENNA,AKH,DEPT GEN & EXPT PATHOL,EBO-3Q,WAEHRINGER GUERTEL 18-20 A-1090 VIENNA AUSTRIA
Titolo Testata:
International archives of allergy and immunology
fascicolo: 2, volume: 116, anno: 1998,
pagine: 83 - 92
SICI:
1018-2438(1998)116:2<83:MAICOL>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
RUBBER ELONGATION-FACTOR; TREE HEVEA-BRASILIENSIS; BIRCH POLLEN ALLERGEN; LYSOZYME CHITINASE ACTIVITY; SPINA-BIFIDA; MASS-SPECTROMETRY; MAJOR ALLERGEN; CLONING; IGE; IDENTIFICATION;
Keywords:
HEVEA BRASILIENSIS; LATEX ALLERGENS; RECOMBINANT ALLERGENS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
59
Recensione:
Indirizzi per estratti:
Citazione:
H. Breiteneder e O. Scheiner, "MOLECULAR AND IMMUNOLOGICAL CHARACTERISTICS OF LATEX ALLERGENS", International archives of allergy and immunology, 116(2), 1998, pp. 83-92

Abstract

Natural rubber latex proteins are a well-recognized cause of type-I allergic reactions that increasingly afflict health-care workers, housekeeping personnel, and other persons using latex gloves or latex products. More than a dozen individual latex allergens have been identifiedof which eight have received an international nomenclature designation. To study the biochemical and immunological properties in detail, itis desirable to clone and express each of these allergens. Proteins that are involved in rubber synthesis are most likely confined to latexwhereas other enzymes, such as chitinases or glucanases, are also present in fruits and may account for the symptoms observed in the latex-fruit syndrome. The available data on the molecular characterization of latex allergens presented here illustrate the importance of this research in the production of better diagnostic tests and, perhaps, toolsfor immunotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 03:50:46