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Titolo:
LUNG UPTAKE OF TL-201 - A MARKER OF DEFECT REVERSIBILITY
Autore:
SANDERSON R; WOLDMAN S; MCCURRACH G; MARTIN W; HUTTON I;
Indirizzi:
ROYAL INFIRM,DEPT MED CARDIOL,16 ALEXANDRA PARADE GLASGOW G31 2ER LANARK SCOTLAND
Titolo Testata:
Physics in medicine and biology
fascicolo: 6, volume: 43, anno: 1998,
pagine: 1469 - 1479
SICI:
0031-9155(1998)43:6<1469:LUOT-A>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; STRESS-REDISTRIBUTION; MYOCARDIAL-ISCHEMIA; VIABLE MYOCARDIUM; TL-201 UPTAKE; HEART RATIO; EXERCISE; SCINTIGRAPHY; REINJECTION; VARIABLES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
R. Sanderson et al., "LUNG UPTAKE OF TL-201 - A MARKER OF DEFECT REVERSIBILITY", Physics in medicine and biology, 43(6), 1998, pp. 1469-1479

Abstract

High lung uptake of thallium-201 at stress is reported to be associated with a large number of perfusion defects and poor prognosis. This study was performed to assess whether the reversibility of stress perfusion defects was related to lung uptake. Gated planar thallium scans at stress and at redistribution from 102 consecutive patients with essentially normal left ventricular ejection fraction (using Tc-99m gated blood pool ventriculography) were graded in terms of defect size. Lungand myocardial uptake of thallium were quantitated by region of interest methods relative to the given activity in a previously validated method. There was no significant correlation (non-parametric) between lung uptake and degree of redistribution (p = ns, r(s) = 0.140). There was a weak but positive correlation between lung uptake and defect size (p < 0.05, r(s) = 0.188). Both exercise time and double product showed a negative correlation with lung uptake (e.g. for double product, p< 0.0005, r(s) = -0.541). In conclusion, contrary to our expectation,lung uptake is not related to the degree of redistribution. High lunguptake seems to reflect poor cardiovascular reserve.

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Documento generato il 03/04/20 alle ore 05:35:02