Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE CLINICAL PICTURE AND THE STABILITY OF NONCOGNITIVE SYMPTOM PATTERNS IN ALZHEIMER PATIENTS
Autore:
HAUPT M; JANNER M; STIERSTORFER A; KRETSCHMAR C;
Indirizzi:
HEINRICH HEINE UNIV,PSYCHIAT KLIN,RHEIN KLINIKEN DUSSELDORF,BERG LANDSTR 2 D-40629 DUSSELDORF GERMANY
Titolo Testata:
Fortschritte der Neurologie, Psychiatrie
fascicolo: 5, volume: 66, anno: 1998,
pagine: 233 - 240
SICI:
0720-4299(1998)66:5<233:TCPATS>2.0.ZU;2-P
Fonte:
ISI
Lingua:
GER
Soggetto:
DEMENTED PATIENTS; FRONTAL-LOBE; DISEASE; DEPRESSION; HYPOMETABOLISM; DISORDERS; MOOD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
M. Haupt et al., "THE CLINICAL PICTURE AND THE STABILITY OF NONCOGNITIVE SYMPTOM PATTERNS IN ALZHEIMER PATIENTS", Fortschritte der Neurologie, Psychiatrie, 66(5), 1998, pp. 233-240

Abstract

The purpose of this study was to investigate noncognitive symptoms inAlzheimer's disease in order to identify symptom patterns and to study stability of such patterns prospectively. Furthermore, variables were examined which could be associated with certain types of symptom patterns or could be predictors of change of these patterns. Forty-eight patients with the clinical diagnosis of probable Alzheimer's disease were included in this study and were assessed weekly over a three-week period. Noncognitive symptoms were rated according to the Behavioral Abnormalities in Alzheimer's Disease Rating Scale (BEHAVE-AD) and the Dementia Mood Assessment Scale (DMAS) and to a set of items specifically assessing misidentifications. By means of principal component factoranalysis different noncognitive symptom patterns were obtained yielding a four-factor solution. They were mapped as rational domains with respect to clinical experience: 'depression', 'apathy', 'psychotic symptoms/aggression', 'misidentifications/agitation'. Demographic and clinical variables were not associated with the factor solutions and did not predict change of the factor values. The results demonstrate that in Alzheimer's disease there are distinct noncognitive symptom patternswith at least short-term prospective stability. None of the examined clinical variables, such as age at entry, the status of the patients (outpatient or inpatient) or dementia severity, exerted substantial influence on the noncognitive symptom patterns. Further investigations should concentrate on the pathological and prognostical correlates of noncognitive symptom patterns in Alzheimer's disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 09:56:49