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Titolo:
THERMAL-ANALYSIS OF BONES FROM OVARIECTOMIZED RATS
Autore:
OKAMOTO Y; HIDAKA S; YAMADA Y; OUCHI K; MIYAZAKI K; LIU SY;
Indirizzi:
FUKUOKA DENT COLL,DEPT DENT MAT,SAWARA KU,2-15-1 TAMURA FUKUOKA 8140193 JAPAN FUKUOKA DENT COLL,DEPT DENT MAT,SAWARA KU FUKUOKA 8140193 JAPAN FUKUOKA COLL HLTH SCI,DEPT DENT HYG,SAWARA KU FUKUOKA 8140193 JAPAN FUKUOKA DENT COLL,DEPT ORAL & MAXILLOFACIAL SURG 1,SAWARA KU FUKUOKA 8140193 JAPAN SHINSHEN NAT OBSERVAT LAB,SAWARA KU FUKUOKA 8140193 JAPAN TSUMURA & CO TOKYO JAPAN
Titolo Testata:
Journal of biomedical materials research
fascicolo: 2, volume: 41, anno: 1998,
pagine: 221 - 226
SICI:
0021-9304(1998)41:2<221:TOBFOR>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESTROGEN; MODEL;
Keywords:
THERMOGRAVIMETRY; DIFFERENTIAL THERMAL ANALYSIS; ACTIVATION ENERGY; OVARIECTOMY; TRADITIONAL CHINESE MEDICINE; 17-BETA-ESTRADIOL; RAT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
Y. Okamoto et al., "THERMAL-ANALYSIS OF BONES FROM OVARIECTOMIZED RATS", Journal of biomedical materials research, 41(2), 1998, pp. 221-226

Abstract

Thermal analyses [thermogravimetry (TG) and differential thermal analysis (DTA)], X-ray diffraction, and infrared absorption analysis of bones from ovariectomized rats were carried out. The rats were divided into five groups: sham operated (Sham); ovariectomized (OVX); OVX giventraditional Chinese (Kampo) medicine, Unkei-to; OVX given 17 beta-estradiol; and OVX given the estradiol vehicle, respectively. The activation energy (Delta E), a kinetic parameter from TG data of OVX rats, increased by 57% from that in Sham rats. The administration of Unkei-to and 17 beta-estradiol to OVX rats clearly restored the Delta E to the levels of Sham rats, while the vehicle for 17 beta-estradiol had no effect. DTA data from thermal analyses of rats from the Sham, OVX, and OVX given various compounds were almost the same except for OVX rats given 17 beta-estradiol. The X-ray diffraction pattern and infrared absorption spectrum of bone powders from Sham rats were not different fromthose of OVX rats or others. These results strongly suggest that a kinetic parameter, Delta E calculated from TG data, may be a useful method for assessing both experimentally induced osteoporosis and drug effects on it. (C) 1998 John Wiley & Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 16:25:10