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Titolo:
ILLICIT DRUG-ASSOCIATED ISCHEMIC STROKE IN THE BALTIMORE-WASHINGTON YOUNG STROKE STUDY
Autore:
SLOAN MA; KITTNER SJ; FEESER BR; GARDNER J; EPSTEIN A; WOZNIAK MA; WITYK RJ; STERN BJ; PRICE TR; MACKO RF; JOHNSON CJ; EARLEY CJ; BUCHHOLZ D;
Indirizzi:
HARBIN CLIN,DEPT NEUROSCI,1825 MARTHA BERRY BLVD ROME GA 00000 UNIV MARYLAND,SCH MED,DEPT NEUROL BALTIMORE MD 21201 UNIV MARYLAND,SCH MED,DEPT EPIDEMIOL & PREVENT MED BALTIMORE MD 21201 EMORY UNIV,SCH MED,DEPT NEUROL ATLANTA GA 30322
Titolo Testata:
Neurology
fascicolo: 6, volume: 50, anno: 1998,
pagine: 1688 - 1693
SICI:
0028-3878(1998)50:6<1688:IDISIT>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEIN-C DEFICIENCY; CARDIAC SOURCE; COCAINE ABUSE; DATA-BANK; ALKALOIDAL COCAINE; INTRANASAL COCAINE; COMPLICATIONS; INFARCTS; EMBOLISM; ADULTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
M.A. Sloan et al., "ILLICIT DRUG-ASSOCIATED ISCHEMIC STROKE IN THE BALTIMORE-WASHINGTON YOUNG STROKE STUDY", Neurology, 50(6), 1998, pp. 1688-1693

Abstract

Background: Limited information exists on the frequency, trends in occurrence, risk factors, mechanisms, and outcome of ischemic stroke associated with illicit drug use among young adults in a geographically defined population. Methods: We reviewed ischemic stroke in young adults (aged 15 to 44 years) in 46 regional hospitals for 1988 and 1991. Weexamined stroke mechanisms and outcome in patients with recent drug use. Results: Recent illicit drug use was noted in 51/422 (12.1%) stroke patients. Patients with drug use were more likely than other stroke patients to be black (p = 0.01), aged 25 to 39 years (p = 0.004), and smokers (p = 0.006), and were less likely to have hypertension (p = 0.004) or diabetes mellitus (p = 0.004). Drug use was the probable causeof stroke in 20 (4.7%) patients. Among 31 (7.3%) patients with drug use as a possible stroke mechanism, more likely diagnoses included cardioembolic stroke in 18, hematologic/collagen vascular in 6, nonatherosclerotic vasculopathy in 5, and atherosclerosis in 3. There was no difference in outcome between drug-associated and non-drug associated stroke. Conclusions: Recent illicit drug use occurs in 12.1% of young adult stroke patients. Drug-associated young adult stroke seems to relateto vascular mechanisms other than those related to hypertension or diabetes. Case-control studies are needed.

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Documento generato il 02/12/20 alle ore 17:26:11