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Titolo:
GERMINAL-CENTERS - FORM AND FUNCTION
Autore:
TARLINTON D;
Indirizzi:
ROYAL MELBOURNE HOSP,WALTER & ELIZA HALL INST MED RES MELBOURNE VIC 3050 AUSTRALIA
Titolo Testata:
Current opinion in immunology
fascicolo: 3, volume: 10, anno: 1998,
pagine: 245 - 251
SICI:
0952-7915(1998)10:3<245:G-FAF>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMORAL IMMUNE-RESPONSE; FOLLICULAR DENDRITIC CELLS; ALPHA-DEFICIENT MICE; T-DEPENDENT ANTIGEN; CENTER B-CELLS; RECEPTOR; LYMPHOTOXIN; MATURATION; EXPRESSION; TOLERANCE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
52
Recensione:
Indirizzi per estratti:
Citazione:
D. Tarlinton, "GERMINAL-CENTERS - FORM AND FUNCTION", Current opinion in immunology, 10(3), 1998, pp. 245-251

Abstract

Our understanding of the formation of germinal centers has advanced considerably during the past year. Highlights include the elucidation of the role of cytokines and chemokines in splenic organization and lymphocyte migration and their roles in germinal center development. The functional consequences of recombination-activating gene re-expressionin the germinal center have also been reported, as have in vitro models of somatic mutation. Finally the resolution of the germinal center reaction is being addressed by analysis of the individual cell types produced.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 07:58:49