Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
IMMEDIATE REPRODUCIBILITY OF UPPER LIMIT OF VULNERABILITY MEASUREMENTS IN PATIENTS UNDERGOING TRANSVENOUS IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR IMPLANTATION
Autore:
ELLENBOGEN KA; WOOD MA; GILLIGAN DM; CROFTS T; LONDON W; MCCLISH D;
Indirizzi:
VIRGINIA COMMONWEALTH UNIV MED COLL VIRGINIA,POB 980053 RICHMOND VA 23298 VIRGINIA COMMONWEALTH UNIV,DEPT MED,DIV CARDIOL RICHMOND VA 23284 VIRGINIA COMMONWEALTH UNIV,DEPT BIOSTAT RICHMOND VA 23284
Titolo Testata:
Journal of cardiovascular electrophysiology
fascicolo: 6, volume: 9, anno: 1998,
pagine: 588 - 595
SICI:
1045-3873(1998)9:6<588:IROULO>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
T-WAVE SHOCKS; VENTRICULAR-FIBRILLATION; THRESHOLD; STRENGTH; HUMANS; EFFICACY; DOGS;
Keywords:
UPPER LIMIT OF VULNERABILITY; DEFIBRILLATION THRESHOLD; REPRODUCIBILITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
K.A. Ellenbogen et al., "IMMEDIATE REPRODUCIBILITY OF UPPER LIMIT OF VULNERABILITY MEASUREMENTS IN PATIENTS UNDERGOING TRANSVENOUS IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR IMPLANTATION", Journal of cardiovascular electrophysiology, 9(6), 1998, pp. 588-595

Abstract

Reproducibility of ULV. Introduction: Measurement of the upper limit of vulnerability (ULV) with monophasic T wave shocks has been proposedas a patient-specific measurement of defibrillation efficacy that results in fewer episodes of ventricular fibrillation (VF) than measurement of a defibrillation efficacy curve. Methods and Results: We sought to determine the magnitude of variance in ULV in 63 consecutive patients undergoing implantation of an implantable cardioverter defibrillator (ICD). We measured ULV as the strength at or above which VF is not induced when a stimulus is delivered at 310 msec after an 8-beat ventricular pacing drive at 400 msec. Defibrillation threshold (DFT) was measured in patients with an active can device using a biphasic waveform and the binary search method beginning at 12 J. Sixty-three patients were studied; they had a mean age of 62 +/- 12 years and a mean ejection fraction of 35% +/- 15%. Three quarters of patients had an ischemic cardiomyopathy. Each patient underwent 4.5 +/- 0.8 measurements of ULV. Monophasic ULV correlated poorly with biphasic DFT (R between 0.19 and 0.28, P = 0.04 to 0.17). There was no change in ULV between second to third, third to fourth, and first to last measurement in 22% to 41%of patients. The reliability coefficient was 0.87. A ULV greater thanor equal to 20 J was found in eight patients. The only predictor of high ULV was a high DFT. Conclusion: Monophasic ULVs do not closely predict biphasic active can DFTs using a standard protocol. High DFTs were predicted by high ULVs. There was little variation in the acute measurement of ULV between trials. These findings have important implications for using ULV measurements to determine changes in DFTs after interventions. The methodology of determining ULV is critical to its use for predicting DFTs and programming ICDs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 03:29:10