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Titolo:
SCREENING OF NEW BIOACTIVE MATERIALS FROM MICROBIAL EXTRACTS OF SOIL MICROORGANISM(I) ANTIMICROBIAL ACTIVITY FROM 200 SAMPLES USING MICRODILUTION ASSAY
Autore:
JUNG SO; KIM J; CHANG IM; RYU JC;
Indirizzi:
KOREA ADV INST SCI & TECHNOL,TOXICOL LAB,POB 131 SEOUL 130650 SOUTH KOREA KOREA ADV INST SCI & TECHNOL,TOXICOL LAB SEOUL 130650 SOUTH KOREA KOREA UNIV,GRAD SCH BIOTECHNOL SEOUL 136701 SOUTH KOREA KOREA UNIV,DIV LIFE SCI SEOUL 136701 SOUTH KOREA SEOUL NATL UNIV,NAT PROD RES INST,CHONGRO KU SEOUL 110460 SOUTH KOREA
Titolo Testata:
Archives of pharmacal research
fascicolo: 3, volume: 21, anno: 1998,
pagine: 278 - 285
SICI:
0253-6269(1998)21:3<278:SONBMF>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
BROTH MICRODILUTION; SUSCEPTIBILITY; METABOLITES; AGENTS; YEASTS;
Keywords:
ANTIBIOTICS; SUSCEPTIBILITY TEST; MICRODILUTION ASSAY; SECONDARY METABOLITES; SOIL MICROORGANISMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
S.O. Jung et al., "SCREENING OF NEW BIOACTIVE MATERIALS FROM MICROBIAL EXTRACTS OF SOIL MICROORGANISM(I) ANTIMICROBIAL ACTIVITY FROM 200 SAMPLES USING MICRODILUTION ASSAY", Archives of pharmacal research, 21(3), 1998, pp. 278-285

Abstract

The microdilution assay recommended by NCCLS (National Committee for Clinical Laboratory Standards) is one of the standardized methods of antibiotic susceptibility test. This method has been widely used clinically to obtain MIC values of antibiotics on pathogenic microorganisms. It is more convinient, rapid and simple to test many samples than other rest methods such as agar diffusion assay and broth macrodilution assay. The screening of antimicrobial agents from microbial extracts istoo laborious in its process. Therefore, a number of screening methods having more simple procedure have been developed. In our laboratory,we applied microdilution assay for screening the antimicrobial agents. This assay showed dose-response results and was more sensitive than disc diffusion assay in our system. We tested 200 samples of microbialextracts originated from 100 microbial strains and selected several samples as potential candidates. In this report, we show that the microdilution assay is more convenient method in screeing of antibiotic susceptibility than those previously reported.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 04:29:11