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Titolo:
THE MEDIAL COCHLEAR EFFERENT SYSTEM DOES NOT APPEAR TO CONTRIBUTE TO THE DEVELOPMENT OF ACQUIRED-RESISTANCE TO ACOUSTIC TRAUMA
Autore:
YAMASOBA T; DOLAN DF;
Indirizzi:
UNIV MICHIGAN,KRESGE HEARING RES INST,1301 E ANN ST ANN ARBOR MI 48109 UNIV MICHIGAN,KRESGE HEARING RES INST ANN ARBOR MI 48109 UNIV TOKYO,DEPT OTOLARYNGOL,BUNKYO KU TOKYO 113 JAPAN
Titolo Testata:
Hearing research
fascicolo: 1-2, volume: 120, anno: 1998,
pagine: 143 - 151
SICI:
0378-5955(1998)120:1-2<143:TMCESD>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
INDUCED HEARING-LOSS; MIDDLE-EAR MUSCLES; CROSSED OLIVOCOCHLEAR BUNDLE; OUTER HAIR-CELLS; NOISE TRAUMA; CONDITIONING EXPOSURES; THRESHOLD SHIFT; STIMULATION; PROTECTION; TEMPORARY;
Keywords:
OLIVOCOCHLEAR BUNDLE; NOISE-INDUCED HEARING LOSS; CONDITIONING; STRYCHNINE; AUDITORY TOUGHENING; GUINEA PIG;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
T. Yamasoba e D.F. Dolan, "THE MEDIAL COCHLEAR EFFERENT SYSTEM DOES NOT APPEAR TO CONTRIBUTE TO THE DEVELOPMENT OF ACQUIRED-RESISTANCE TO ACOUSTIC TRAUMA", Hearing research, 120(1-2), 1998, pp. 143-151

Abstract

Noise-induced hearing loss (NIHL) was compared between sound conditioned and unconditioned guinea pigs, in which the left ear in both groups had been perfused with strychnine. Animals in the conditioned group were subjected to moderate sound (85 dB SPL broadband, 5 h/day, 10 days) and then exposed to intense sound (110 dB sPL broadband, 5 h). Unconditioned animals were exposed only to the intense sound. Following intense sound exposure, strychnine-treated ears showed greater NIHL thanuntreated ears in both unconditioned and conditioned animals, demonstrating the role of the medial efferents to reduce NIHL. Conditioned animals, however, showed smaller hearings loss and cochlear damage in both strychnine-treated and untreated ears compared to unconditioned animals; the protective effects given by conditioning were equivalent between the strychnine-treated and untreated ears. These results suggest that, although the medial efferent system acts to attenuate NIHL. it may not be necessary for. the acquired resistance to NIHL provided by conditioning. (C) 1998 Elsevier Science B.V. All rights reserved.

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Documento generato il 04/12/20 alle ore 09:37:36