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Titolo:
DIAGNOSTIC THORACIC-COMPUTED TOMOGRAPHY IN RADIOTHERAPY FOR LOCO-REGIONAL RECURRENT BREAST-CARCINOMA
Autore:
CHENG JC; CHENG SH; LIN KJ; JIAN JJ; CHAN KY; HUANG AT;
Indirizzi:
KOO FDN SUN YAT SEN CANC CTR,DEPT RADIAT ONCOL,125 LIH DER RD,PEI TOUTAIPEI 112 TAIWAN KOO FDN SUN YAT SEN CANC CTR,DEPT DIAGNOST RADIOL TAIPEI 112 TAIWAN KOO FDN SUN YAT SEN CANC CTR,DEPT MED ONCOL TAIPEI 112 TAIWAN DUKE UNIV,MED CTR,DEPT INTERNAL MED DURHAM NC 27710
Titolo Testata:
International journal of radiation oncology, biology, physics
fascicolo: 3, volume: 41, anno: 1998,
pagine: 607 - 613
SICI:
0360-3016(1998)41:3<607:DTTIRF>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTERNAL MAMMARY LYMPHOSCINTIGRAPHY; CHEST WALL RECURRENCES; POSTOPERATIVE RADIOTHERAPY; ADJUVANT CHEMOTHERAPY; RADIATION-THERAPY; CANCER RECURRENCE; CT EVALUATION; MASTECTOMY; IRRADIATION; NODES;
Keywords:
LOCO-REGIONAL RECURRENT BREAST CARCINOMA; COMPUTED TOMOGRAPHY; RADIOTHERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
J.C. Cheng et al., "DIAGNOSTIC THORACIC-COMPUTED TOMOGRAPHY IN RADIOTHERAPY FOR LOCO-REGIONAL RECURRENT BREAST-CARCINOMA", International journal of radiation oncology, biology, physics, 41(3), 1998, pp. 607-613

Abstract

Purpose: This study was initiated to evaluate whether pretreatment diagnostic thoracic CT scan was useful for patients with loco-regional recurrent breast carcinoma, and to assess its impact on the design of radiotherapeutic treatment. Methods and Materials: Between March 1991 and January 1997, 44 patients underwent thoracic CT examination with contrast material before the consideration of radiotherapy for their isolated loco-regional recurrent breast carcinoma. The CT radiographs were prospectively reviewed for additional findings clinically undetectedby prior physical examination and plain-chest radiograph, The changesmade in treatment design and dosage of radiation as a result of CT findings were recorded for analysis. The correlation between prognostic indicators and the CT findings was also studied. Results: Twenty-two of 44 (50%) patients were found to have additional abnormalities detected only after thoracic CT examinations were performed. The strategy ofradiation therapy was altered in 17 of 22 (77%) patients as a result. Patients with shorter disease-free interval (p = 0.08) and multiple sites of recurrence (p = 0.05) tended to have greater numbers of findings on CT scan previously unsuspected, Thus, CT scan is a valuable guide to treating loco-regional recurrent disease. Conclusion: Pretreatment diagnostic thoracic CT scan offers essential information that can alter treatment planning and thus optimize treatment strategy for a large proportion of patients with clinically isolated loco-regional recurrent breast carcinoma. In this population of patients we recommend thatthoracic CT examination be considered before the initiation of radiation therapy. (C) 1998 Elsevier Science Inc.

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Documento generato il 06/07/20 alle ore 07:48:33