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Titolo:
FIRST-PASS RADIONUCLIDE ANGIOGRAPHY USING I-123 MYOCARDIAL TRACERS AND A MULTICRYSTAL GAMMA-CAMERA
Autore:
TADAMURA E; KITANO H; KUDOH T; HATTORI N; INUBUSHI M; NISHIMURA K; MASUDA I; INADA H; HOSOKAWA R; NOHARA R; KONISHI J;
Indirizzi:
KYOTO UNIV,FAC MED,DEPT NUCL MED & DIAGNOST IMAGING,SAKYO KU KYOTO 60601 JAPAN KYOTO UNIV,FAC MED,DEPT NUCL MED KYOTO JAPAN KYOTO UNIV,FAC MED,DEPT CARDIOVASC SURG,DIV 2 KYOTO JAPAN KYOTO UNIV,FAC MED,DEPT CARDIOVASC SURG,DIV 3 KYOTO JAPAN KYOTO UNIV,FAC MED,DEPT INTERNAL MED KYOTO JAPAN
Titolo Testata:
The Journal of nuclear medicine
fascicolo: 6, volume: 39, anno: 1998,
pagine: 938 - 944
SICI:
0161-5505(1998)39:6<938:FRAUIM>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR EJECTION FRACTION; CORONARY-ARTERY DISEASE; GATED BLOOD-POOL; PROGNOSTIC VALUE; HEART-FAILURE; FATTY-ACIDS; EXERCISE; ANGIOCARDIOGRAPHY; PERFUSION; SPECT;
Keywords:
I-123 MYOCARDIAL TRACER; FIRST-PASS RADIONUCLIDE ANGIOGRAPHY; EJECTION FRACTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
E. Tadamura et al., "FIRST-PASS RADIONUCLIDE ANGIOGRAPHY USING I-123 MYOCARDIAL TRACERS AND A MULTICRYSTAL GAMMA-CAMERA", The Journal of nuclear medicine, 39(6), 1998, pp. 938-944

Abstract

The purpose of this study was to validate the accuracy of the assessment of ventricular function by first-pass radionuclide angiography (FPRNA) with I-123 myocardial tracers and a multicrystal gamma camera. Methods: Left ventricular ejection fraction (LVEF) and right ventricularejection fraction were measured in 69 patients by FPRNA using I-123 myocardial tracers (126 +/- 7 MBq) and Tc-99m tracers (541 +/- 141 MBq)on a multicrystal gamma camera with a high-sensitivity collimator. For 44 patients, ejection fraction values measured by I-123-FPRNA were compared to those estimated by equilibrium radionuclide angiography (ERNA). Visual wall-motion analysis was also performed to judge clinical acceptability of I-123- FPRNA images for identification of wall-motionabnormality, Results: Mean LVEFs (%) estimated by I-123-FPRNA and by Tc-99m- FPRNA were 49.6 +/- 13.6 and 49.1 +/- 14.1, respectively (nonsignificant p value). An excellent correlation was found between LVEFs estimated by I-123-FPRNA and Tc-99m-FPRNA (r = 0.96, s.e.e. = 1.9%). Values of LVEF measured by I-123-FPRNA also demonstrated excellent correlation with those measured by ERNA (r 0.95, s.e.e. = 2.2%). A good correlation was also noted between right ventricular ejection fractions measured by I-123-FPRNA and Tc-99m-FPRNA (r = 0.72, s.e.e. = 4.0%). The Spearman rank correlation coefficient between I-123-FPRNA and ERNA wall-motion scores was 0.87 (n = 135, p < 0.001). Conclusion: Resting ventricular function can be reliably measured with I-123-FPRNA in combination with a multicrystal gamma camera. This indicates that the assessment of ventricular function is feasible in conjunction with I-123 myocardial imaging without an increase in cost or radiation dose to patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 23:04:29