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Titolo:
PROCALCITONIN IN EARLY DETECTION OF POSTOPERATIVE COMPLICATIONS
Autore:
REITH HB; MITTELKOTTER U; DEBUS ES; KUSSNER C; THIEDE A;
Indirizzi:
UNIV WURZBURG,DEPT SURG,CLIN & POLICLIN SURG,JOSEF SCHNEIDER STR 2 D-97080 WURZBURG GERMANY
Titolo Testata:
Digestive surgery
fascicolo: 3, volume: 15, anno: 1998,
pagine: 260 - 265
SICI:
0253-4886(1998)15:3<260:PIEDOP>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERUM PROCALCITONIN; SEPSIS; INTERLEUKIN-6;
Keywords:
ELECTIVE SURGERY; POSTOPERATIVE COMPLICATIONS; CYTOKINES; PROCALCITONIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
H.B. Reith et al., "PROCALCITONIN IN EARLY DETECTION OF POSTOPERATIVE COMPLICATIONS", Digestive surgery, 15(3), 1998, pp. 260-265

Abstract

Background: A prospective clinical study was performed to assess the accuracy of procalcitonin in 70 patients with elective colorectal or aortal surgery and to compare it with inflammatory mediators. Also the early prediction of complications and the outcome of these patients was taken into account, Methods: Laboratory variables and cytokine determination were obtained preoperatively on the day of operation and postoperatively on a daily basis from day 1 to 5, and on days 7 and early recognition of complications and alterations in the production of procalcitonin and cytokines in order to detect severe infective complications. Results: Procalcitonin was closely related to postoperative complications with significantly elevated levels at day 1 after surgery. The plasma concentrations of IL-6 increase on days 1-3 without a difference in the groups, also C-reactive protein demonstrates no differences. Conclusion: Procalcitonin presents itself as a new parameter of infection and sepsis. In the postoperative period PCT seems to be an interesting marker of early prediction of infective complications when highpostoperative levels are found. Under routine conditions procalcitonin is a valid reproducible and detectable parameter.

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Documento generato il 11/07/20 alle ore 10:07:47