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Titolo:
MACAQUE MDC FAMILY OF PROTEINS - SEQUENCE-ANALYSIS, TISSUE DISTRIBUTION AND PROCESSING IN THE MALE REPRODUCTIVE-TRACT
Autore:
FRAYNE J; JURY JA; BARKER HL; PERRY ACF; JONES R; HALL L;
Indirizzi:
UNIV BRISTOL,SCH MED SCI,DEPT BIOCHEM BRISTOL BS8 1TD AVON ENGLAND UNIV BRISTOL,SCH MED SCI,DEPT BIOCHEM BRISTOL BS8 1TD AVON ENGLAND BABRAHAM INST,BBSRC,DEPT SIGNALLING CAMBRIDGE CB2 4AT ENGLAND
Titolo Testata:
Molecular human reproduction
fascicolo: 5, volume: 4, anno: 1998,
pagine: 429 - 437
SICI:
1360-9947(1998)4:5<429:MMFOP->2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPERM-EGG FUSION; METALLOPROTEASE-DISINTEGRIN PROTEIN; SEMINIFEROUS EPITHELIUM; RAT SPERMATOZOA; POTENTIAL ROLE; FERTILIZATION; EXPRESSION; SUBUNIT; DOMAIN; IDENTIFICATION;
Keywords:
MDC PROTEINS; METALLOPROTEINASE-LIKE DISINTEGRIN-LIKE CYSTEINE-RICH PROTEINS; SPERMATOZOA; SPERM ANTIGENS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
45
Recensione:
Indirizzi per estratti:
Citazione:
J. Frayne et al., "MACAQUE MDC FAMILY OF PROTEINS - SEQUENCE-ANALYSIS, TISSUE DISTRIBUTION AND PROCESSING IN THE MALE REPRODUCTIVE-TRACT", Molecular human reproduction, 4(5), 1998, pp. 429-437

Abstract

A large number of sequence-related, cysteine-rich membrane proteins containing metalloproteinase-like and disintegrin-like domains (the MDCprotein family) have been identified in mammalian tissues from a variety of species. Previous studies in the macaque (Macaca fascicolaris) have led to the cDNA cloning and sequence analysis of a number of MDC proteins which are abundantly expressed in the male reproductive tract. We now describe the distribution of seven of these macaque MDC transcripts in a range of different tissues. This description includes a novel macaque testis-derived MDC, tMDC III, whose full-length sequence is reported for the first time. In addition, polyclonal antisera have been used to localize a number of these MDC proteins to spermatogenic cells in testis sections, and to demonstrate their processing on the sperm surface during epididymal transit.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 06:15:00