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Titolo:
IN-HOSPITAL AND LATE RESULTS OF CORONARY STENTS VERSUS CONVENTIONAL BALLOON ANGIOPLASTY IN ACUTE MYOCARDIAL-INFARCTION (GRAMI TRIAL)
Autore:
RODRIGUEZ A; BERNARDI V; FERNANDEZ M; MAUVECIN C; AYALA F; SANTAERA O; MARTINEZ J; MELE E; ROUBIN GS; PALACIOS I; AMBROSE JA;
Indirizzi:
AYACUCHO 1547 10 B RA-1112 BUENOS AIRES DF ARGENTINA ANCHORENA HOSP,CARDIAC UNIT OTAMENDI BUENOS AIRES DF ARGENTINA UNIV ALABAMA,CARDIAC UNIT BIRMINGHAM AL 00000 MASSACHUSETTS GEN HOSP,CARDIAC UNIT BOSTON MA 02114 MT SINAI HOSP,CARDIOVASC INST NEW YORK NY 10029
Titolo Testata:
The American journal of cardiology
fascicolo: 11, volume: 81, anno: 1998,
pagine: 1286 - 1291
SICI:
0002-9149(1998)81:11<1286:IALROC>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
THROMBOLYTIC THERAPY; LUMINAL DIAMETER; ARTERY DISEASE; IMMEDIATE ANGIOPLASTY; THREATENED CLOSURE; IMPLANTATION; RESTENOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
A. Rodriguez et al., "IN-HOSPITAL AND LATE RESULTS OF CORONARY STENTS VERSUS CONVENTIONAL BALLOON ANGIOPLASTY IN ACUTE MYOCARDIAL-INFARCTION (GRAMI TRIAL)", The American journal of cardiology, 81(11), 1998, pp. 1286-1291

Abstract

One hundred four patients presenting with acute myocardial infarction<24 hours after onset were randomized to 2 groups: group I (n = 52) was treated with balloon angioplasty followed electively with GianturcoRoubin II stents, and group II was treated with conventional balloon angioplasty alone (n = 52). All lesions were suitable for stenting. Baseline clinical, demographic, and angiographic characteristics were similar in the 2 groups. Procedural success was defined as no laboratorydeath or emergent coronary bypass, Thrombolysis In Myocardial Infarction (TIMI) trial 2 or 3 flow after the procedure in a culprit vessel, and a residual stenosis less than or equal to 30% for coronary angioplasty and <20% for stent. Procedural success was 98% in group I versus 94.2% in group II, p = NS. Thirteen patients in group II (25%) had bailout stenting during the initial procedure. Adverse in-hospital eventsincluding either death, non-elective coronary bypass, recurrent ischemia, and reinfarction occurred in 3.8% in group I versus 19.2% in group II, p = 0.03. Repeat angiography performed routinely before hospitaldischarge revealed TIMI 3 flow in the infarct-related artery in 98% in group I versus 83% in group II, p <0.03. At late follow-vp, event-free survival was significantly better in the stent (83%) than in the coronary angioplasty (65%) group (p = 0.002). The procedural in-hospitaland late outcomes of this randomized study demonstrate that balloon angioplasty followed electively by coronary stents can be used as the primary modality for patients undergoing coronary interventions for acute myocardial infarction, increasing TIMI 3 flow, reducing in-hospitaladverse events, and improving late outcome compared with balloon angioplasty alone. (C) 1998 by Excerpta Medico, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 07:32:09