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Titolo:
BLOOD CADMIUM LEVELS IN NONEXPOSED MALE-SUBJECTS LIVING IN THE ROME AREA - RELATIONSHIP TO SELECTED CARDIOVASCULAR RISK-FACTORS
Autore:
MENDITTO A; CHIODO F; PATRIARCA M; MORISI G; MENOTTI A; SPAGNOLO A;
Indirizzi:
IST SUPER SANITA,BIOCHIM CLIN LAB,VIALE REGINA ELENA 299 I-00161 ROMEITALY IST SUPER SANITA,EPIDEMIOL & BIOSTAT LAB I-00161 ROME ITALY ASSOC RIC CARDIOL CARDIORIC ROME ITALY
Titolo Testata:
Microchemical journal
fascicolo: 1, volume: 59, anno: 1998,
pagine: 173 - 179
SICI:
0026-265X(1998)59:1<173:BCLINM>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENVIRONMENTAL EXPOSURE; GENERAL-POPULATION; HUMAN HYPERTENSION; TRACE-ELEMENTS; LEAD; PRESSURE; TIME;
Keywords:
BLOOD CADMIUM; CIGARETTE SMOKING; ALCOHOL CONSUMPTION; BLOOD PRESSURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
A. Menditto et al., "BLOOD CADMIUM LEVELS IN NONEXPOSED MALE-SUBJECTS LIVING IN THE ROME AREA - RELATIONSHIP TO SELECTED CARDIOVASCULAR RISK-FACTORS", Microchemical journal, 59(1), 1998, pp. 173-179

Abstract

Blood cadmium (B-Cd) levels were determined in non-occupationally exposed men aged 55-75 years living in the Rome area (Italy) who participated in an epidemiological survey for coronary heart disease (New RiskFactors Project). Among the subjects considered in this study (n = 1223), the geometric mean and the geometric standard deviation for B-Cd were 4.58 and 1.84 nmol/liter, respectively. In never smoked and current smokers, the geometric means (geometric standard deviation) for B-Cd were 2.98 nmol/liter (1.61 nmol/liter) and 7.83 nmol/liter (1.68 nmol/liter), respectively. In linear regression analysis B-Cd levels weresignificantly and positively associated with daily cigarette consumption (r = 0.5501, P < 0.0001), alcohol consumption (g/day; r = 0.1033, P = 0.0003), non-high-density-lipoprotein cholesterol levels (mmol/liter; r = 0.0848, P = 0.0030), triglyceride levels (mmol/liter, after log-normal transformation; r = 0.0695, P = 0.0151), and blood lead levels (mu mol/liter, after log-normal transformation; r = 0.2506, P < 0.0001). B-Cd levels were inversely related to skinfold thicknesses (mm; r= -0.1094, P < 0.0001), body mass index (kg/m(2); r = -0.0482, P = 0.0922), and diastolic blood pressure (mm Hg; r = -0.0638, P = 0.0257). No linear correlation was found between B-Cd and systolic blood pressure or mean blood pressure. In multiple regression analysis daily cigarette consumption and blood lead levels were significant predictors of B-Cd level explaining 30.26 and 2.86% of total variance, respectively. B-Cd was not a significant predictor of diastolic, systolic, or mean blood pressure in multiple regression analyses. (C) 1998 Academic Press.

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Documento generato il 03/04/20 alle ore 07:56:24