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Titolo:
An efficient copper-catalyzed coupling of aryl halides with imidazoles
Autore:
Kiyomori, A; Marcoux, JF; Buchwald, SL;
Indirizzi:
MIT, Dept Chem, Cambridge, MA 02139 USA MIT Cambridge MA USA 02139MIT, Dept Chem, Cambridge, MA 02139 USA
Titolo Testata:
TETRAHEDRON LETTERS
fascicolo: 14, volume: 40, anno: 1999,
pagine: 2657 - 2660
SICI:
0040-4039(19990402)40:14<2657:AECCOA>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIOTONIC AGENTS; PHOSPHODIESTERASE; DERIVATIVES; INHIBITORS; 4,5-DIHYDRO-6-<4-(1H-IMIDAZOL-1-YL)PHENYL>-3(2H)-PYRIDAZINONES; SYNTHASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Buchwald, SL MIT, Dept Chem, Cambridge, MA 02139 USA MIT Cambridge MA USA02139 ept Chem, Cambridge, MA 02139 USA
Citazione:
A. Kiyomori et al., "An efficient copper-catalyzed coupling of aryl halides with imidazoles", TETRAHEDR L, 40(14), 1999, pp. 2657-2660

Abstract

Copper-catalyzed N-arylation of imidazoles can be accomplished using (CuOTf)(2). benzene as a copper source and Cs2CO3 as a base in xylenes at 110-125 degrees C. Addition of l,l0-phenanthroline (phen) and trans, trans-dibenzylideneacetone (dba) was crucial to the success of the process. The products, N-arylimidazoles, were isolated in high yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 10:37:18