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Titolo:
Tissue reactions to polyethylene implants with different surface topography
Autore:
Rosengren, A; Bjursten, LM; Danielsen, N; Persson, H; Kober, M;
Indirizzi:
Univ Hosp MAS, Dept Expt Res, S-20502 Malmo, Sweden Univ Hosp MAS Malmo Sweden S-20502 Dept Expt Res, S-20502 Malmo, Sweden Univ Lund Hosp, Dept Physiol & Neurosci, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 siol & Neurosci, S-22185 Lund, Sweden Univ Lund, Ctr Chem, Dept Chem Engn 2, S-22100 Lund, Sweden Univ Lund Lund Sweden S-22100 em, Dept Chem Engn 2, S-22100 Lund, Sweden
Titolo Testata:
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
fascicolo: 2, volume: 10, anno: 1999,
pagine: 75 - 82
SICI:
0957-4530(199902)10:2<75:TRTPIW>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIFFERENT OXIDE THICKNESSES; COMMERCIALLY PURE TITANIUM; BONE RESPONSE; ELECTROPOLISHED IMPLANTS; ABDOMINAL-WALL; CELL-SHAPE; BIOMATERIAL; MACROPHAGE; INTEGRATION; INTERFACE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Rosengren, A Univ Hosp MAS, Dept Expt Res, S-20502 Malmo, Sweden Univ HospMAS Malmo Sweden S-20502 s, S-20502 Malmo, Sweden
Citazione:
A. Rosengren et al., "Tissue reactions to polyethylene implants with different surface topography", J MAT S-M M, 10(2), 1999, pp. 75-82

Abstract

This study investigates the importance of implant surface topography on soft tissue response. The tissue response in the rat abdominal wall to discs of low density polyethylene with smooth to coarse surfaces was evaluated after one, six or 12 weeks. Capsule thickness and immunohistochemical quantification of monocytes-macrophages were used as measures. The macrophage specific antibody ED1 was used for identification of newly recruited macrophages and the ED2 antibody for the mature tissue macrophages. The smoother surfaces gave a thicker capsule than the rougher surfaces, and at one week alsolarger total numbers of cells and ED1 positive macrophages at interface. The capsule thickness increased over time for the smooth and intermediate surface topographies. In contrast, the cell numbers generally decreased over time. In conclusion, a coarse surface elicited lesser tissue reaction compared with a smooth surface, (C) 1999 Kluwer Academic Publishers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/01/21 alle ore 22:32:22