Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Geography of intestinal permeability and absorption
Autore:
Menzies, IS; Zuckerman, MJ; Nukajam, WS; Somasundaram, SG; Murphy, B; Jenkins, AP; Crane, RS; Gregory, GG;
Indirizzi:
Texas Tech Univ, Hlth Sci Ctr, Dept Med, El Paso, TX 79905 USA Texas Tech Univ El Paso TX USA 79905 Ctr, Dept Med, El Paso, TX 79905 USA UnivEngland Kings Coll, Sch Med & Dent, Dept Clin Biochem, London SE5 9PJ,Univ London Kings Coll London England SE5 9PJ n Biochem, London SE5 9PJ, St Thomas Hosp, London SE1 7EH, England St Thomas Hosp London England SE1 7EH omas Hosp, London SE1 7EH, England Univ Texas, Dept Math Sci, El Paso, TX 79968 USA Univ Texas El Paso TX USA 79968 xas, Dept Math Sci, El Paso, TX 79968 USA
Titolo Testata:
GUT
fascicolo: 4, volume: 44, anno: 1999,
pagine: 483 - 489
SICI:
0017-5749(199904)44:4<483:GOIPAA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
SMALL-BOWEL MORPHOLOGY; QUANTITATIVE ESTIMATION; ACUTE GASTROENTERITIS; TROPICAL ENTEROPATHY; TRAVELERS DIARRHEA; CR-51 EDTA; CHROMATOGRAPHY; MALABSORPTION; PERMEATION; HAITIANS;
Keywords:
intestinal permeability; absorption; tropical enteropathy; non-invasive sugar absorption/permeability test;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Zuckerman, MJ Texas5Tech Univ, Hlth Sci Ctr, Dept Med, 4800 Alberta Ave, El Paso, TX 7990 Texas Tech Univ 4800 Alberta Ave El Paso TX USA 79905 X 7990
Citazione:
I.S. Menzies et al., "Geography of intestinal permeability and absorption", GUT, 44(4), 1999, pp. 483-489

Abstract

Background-Intestinal morphology and function vary geographically. Aims-These functions were assessed in asymptomatic volunteers in European,North American, Middle Eastern, Asian, African, and Caribbean countries. Methods-Five hour urine collections were obtained from each subject following ingestion of a 100 ml iso-osmolar test solution containing 3-0-methyl-D-glucose, D-xylose, L-rhamnose, and lactulose after an overnight fast, to assess active (3-0-methyl-D-glucose) and passive (D-xylose) carrier mediated, and non-mediated (L-rhamnose) absorption capacity, as well as intestinal permeability (lactulose:rhamnose ratio). Results-A comparison of results for subjects from tropical countries (n=218) with those resident in the combined temperate and subtropical region (Europe, United States, Qatar) (n=224) showed significant differences. Residents in tropical areas had a higher mean lactulose:rhamnose ratio and lower mean five hour recoveries of 3-0-methyl-D-glucose, D-xylose, and L-rhamnose,indicating higher intestinal permeability and lower absorptive capacity. Investigation of visiting residents suggested that differences in intestinalpermeability and absorptive capacity were related to the area of residence. Subjects from Texas and Qatar, although comprised of several ethnic groups and resident in a subtropical area, showed no significant difference fromEuropean subjects. Conclusions-There are clearly demarcated variations in intestinal permeability and absorptive capacity affecting asymptomatic residents of different geographical areas which correspond with the condition described as tropical enteropathy. Results suggest the importance of environmental factors. Theparameters investigated may be relevant to the predisposition of the indigenous population and travellers to diarrhoeal illness and malnutrition. Intestinal function in patients from the tropics may be difficult to interpret, but should take into account the range of values found in the asymptomatic normal population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 09:09:58