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Titolo:
Interaction of S-SCAM with neural plakophilin-related armadillo-repeat protein/delta-catenin
Autore:
Ide, N; Hata, Y; Deguchi, M; Hirao, K; Yao, I; Takai, Y;
Indirizzi:
Osaka Univ, Sch Med, Dept Mol Biol & Biochem, Suita, Osaka 5650871, Japan Osaka Univ Suita Osaka Japan 5650871 Biochem, Suita, Osaka 5650871, Japan JCRorp,rmacuet Co Ltd, Takai Biotimer Project, ERATO, Japan Sci & Technol C JCR Pharmacuet Co Ltd Kobe Hyogo Japan 6512241 ATO, Japan Sci & Technol C
Titolo Testata:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
fascicolo: 3, volume: 256, anno: 1999,
pagine: 456 - 461
SICI:
0006-291X(19990324)256:3<456:IOSWNP>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
DESMOSOMAL PLAQUE; MULTIGENE FAMILY; BAND-6 PROTEIN; DOMAIN; MEMBER; IDENTIFICATION; LOCALIZATION; PLAKOGLOBIN; RECEPTORS; CHANNEL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Takai, Y Osaka5650871,ch Med, Dept Mol Biol & Biochem, 2-2 Yamada Oka, Suita, Osaka Osaka Univ 2-2 Yamada Oka Suita Osaka Japan 5650871 Suita, Osaka
Citazione:
N. Ide et al., "Interaction of S-SCAM with neural plakophilin-related armadillo-repeat protein/delta-catenin", BIOC BIOP R, 256(3), 1999, pp. 456-461

Abstract

Synaptic scaffolding molecule (S-SCAM) is a multiple PDZ domain-containingprotein, which interacts with neuroligin, a cell adhesion molecule, and the NMDA receptor. In this study, we searched for S-SCAM-interacting proteinsand obtained a neural plakophilin-related armadillo-repeat protein (NPRAP)/delta-catenin, NPRAP/delta-catenin bound to the last PDZ domain of S-SCAM via its carboxyl-terminus in three different cell-free assay systems, was coimmunoprecipitated with S-SCAM from rat crude synaptosomes, and was localized at the excitatory synapses in rat hippocampal neurons. NPRAP/delta-catenin may be implicated in the molecular organization of synaptic junctions through the interaction with S-SCAM, (C) 1999 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 07:14:21