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Titolo:
LASER WIRE FOR CROSSING CHRONIC TOTAL OCCLUSIONS - LEARNING PHASE RESULTS FROM THE US TOTAL TRIAL
Autore:
OESTERLE SN; BITTL JA; LEON MB; HAMBURGER J; TCHENG JE; LITVACK F; MARGOLIS J; GILMORE P; MADSEN R; HOLMES D; MOSES J; COHEN H; KING S; BRINKER J; HALE T; GERACI DJ; KERKER WJ; POPMA J;
Indirizzi:
STANFORD UNIV,MED CTR,DEPT MED,DIV CARDIOVASC MED,2103 STANFORD CA 94305 HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,DEPT MED BOSTON MA 02115 WASHINGTON HOSP CTR,DEPT MED WASHINGTON DC 20010 ERASMUS UNIV,CTR THORAX,DEPT MED NL-3000 DR ROTTERDAM NETHERLANDS DUKE UNIV,MED CTR,DEPT MED DURHAM NC 27710 CEDARS SINAI MED CTR,DEPT MED LOS ANGELES CA 90048 MIAMI HEART INST,DEPT MED MIAMI FL 00000 UNIV MED CTR,DEPT MED JACKSONVILLE FL 00000 JEWISH HOSP,DEPT MED LOUISVILLE KY 00000 MAYO CLIN,DEPT MED ROCHESTER MN 00000
Titolo Testata:
Catheterization and cardiovascular diagnosis
fascicolo: 2, volume: 44, anno: 1998,
pagine: 235 - 243
SICI:
0098-6569(1998)44:2<235:LWFCCT>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUMINAL CORONARY ANGIOPLASTY; BALLOON ANGIOPLASTY; ARTERY OCCLUSION; SHORT-TERM; FOLLOW-UP; GLIDEWIRE; SUCCESS; EXPERIENCE; RESTENOSIS; REGISTRY;
Keywords:
ANGIOPLASTY; LASER; GUIDEWIRE; CHRONIC TOTAL OCCLUSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
S.N. Oesterle et al., "LASER WIRE FOR CROSSING CHRONIC TOTAL OCCLUSIONS - LEARNING PHASE RESULTS FROM THE US TOTAL TRIAL", Catheterization and cardiovascular diagnosis, 44(2), 1998, pp. 235-243

Abstract

The Prima(TM) laser guidewire system (Spectranectics Corp., Colorado Springs, CO) consists of an 0.018 '' hypotube containing a bundle of 45-mu m optical fibers coupled to a pulsed excimer laser operating at atip fluence of 60 ml/mm(2) and a repetition rate ranging from 25-40 Hz, This laser guidewire was specifically designed to cross total occlusions refractory to passage with conventional wires. The Prima wire was evaluated in a feasibility study at 15 U.S. centers. Following failure to cross a total occlusion with approved guidewires, the Prima wirewas utilized in 179 patients. Average age of subjects was 61 yr. Lesion locations included left anterior descending (36%), right (45%), andcircumflex (19%) coronary arteries. Mean angiographic age of total occlusions was 70 wk (range, 2-1,020 wk, median, 14 wk). The use of the Prima wire either solely or in combination with conventional guidewires resulted in successful crossing in 61% of these previously impenetrable occlusions. Failure of the device was commonly related to length of the occlusion and tortuosity along the occluded pathway. Major complications included myocardial infarction in 7 patients (3.9%), tamponade in 3 (1.7%), and death in 2 (1.1%). This ''learning phase'' pilot study confirmed the feasibility of a laser guidewire in chronic total occlusions that are resistant to passage of conventional guidewires. An extended registry at these investigative sites is planned. (C) 1998 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 01:06:04