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Titolo:
THE COMPARISON OF 4 WEIGHT-REDUCTION STRATEGIES AIMED AT OVERWEIGHT PATIENTS WITH DIABETES-MELLITUS - 4-YEAR FOLLOW-UP
Autore:
MANNING RM; JUNG RT; LEESE GP; NEWTON RW;
Indirizzi:
NINEWELLS HOSP,CTR DIABET DUNDEE DD1 9SY SCOTLAND NINEWELLS HOSP,CTR DIABET DUNDEE DD1 9SY SCOTLAND
Titolo Testata:
Diabetic medicine
fascicolo: 6, volume: 15, anno: 1998,
pagine: 497 - 502
SICI:
0742-3071(1998)15:6<497:TCO4WS>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEXFENFLURAMINE; OBESITY;
Keywords:
DIABETES MELLITUS; OBESITY; DEXFENFLURAMINE; HOME VISITS; DIETITIAN; BEHAVIORAL THERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
R.M. Manning et al., "THE COMPARISON OF 4 WEIGHT-REDUCTION STRATEGIES AIMED AT OVERWEIGHT PATIENTS WITH DIABETES-MELLITUS - 4-YEAR FOLLOW-UP", Diabetic medicine, 15(6), 1998, pp. 497-502

Abstract

Weight change and glycaemic control in 132 diabetic patients previously treated for 1 year by four different methods aimed at weight loss were reanalysed 4 years after the outset. The four treatment groups comprised clinic visits, home visits, behavioural group therapy, and dexfenfluramine given for the initial 3 months followed by clinic visits. When analysed on an intention to treat basis only the dexfenfluramine group maintained a significant weight loss at year 4 (mean -2.46 kg) with 43% of patients losing 3 kg or more; HBA(1c) was not decreased. The other treatment groups showed overall weight regain from year 1 to year 4. Within the home visit group however, the number of patients losing at least 3 kg doubled between years 1 (21%) and 4 (38%). When analysed on a completion basis, weight loss in the dexfenfluramine group was significant in females but not in males at year 4. During the 4 years of observation a cohort of 54 patients reflecting our routine clinic practice gained on average 0.35 kg. Although now withdrawn, the use of an appetite suppressant dexfenfluramine for just 3 months would appear to have a long-term advantage on weight loss in this diabetic population, although the weight lost was not associated with improvement in glycaemic control. (C) 1998 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 09:20:58